2-[(E)-dodec-6-en-11-yn-5-yl]-1,1-diphenylhydrazine | 1226885-90-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[(E)-dodec-6-en-11-yn-5-yl]-1,1-diphenylhydrazine
• CAS: 1226885-90-0
• 化学式: C₂₄H₃₀N₂
• 分子量: 346.516
• InChiKey: STZJEELYOCHESK-GZTJUZNOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  26
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-[(E)-dodec-6-en-11-yn-5-yl]-1,1-diphenylhydrazine 在 偶氮二异丁腈 、 三正丁基氢锡 作用下， 以 苯 为溶剂， 生成 、 1-[(E)-hex-1-enyl]-2-methylidenecyclopentane
  参考文献：
  名称：

  Novel Radical Cyclization Method Accompanied by Elimination of Hydrazyl Radical

  摘要：

  The potential of hydrazine group as the new radical leaving group was studied. Radical cyclization of (E)-1,1-dialkyl-2-(1-alkyloct-2-en-7-ynyl)hydrazines with n-Bu(3)SnH/AIBN, followed by protodestannylation, gave 1-alkenyl-2-methylenecyclopentanes, which arose by 5-exo cyclization and subsequent beta-elimination of hydrazyl radical.

  DOI：

  10.3987/com-09-s(s)115
• 作为产物：
  描述：

  正丁基锂 、 以 乙醚 为溶剂， 生成 2-[(E)-dodec-6-en-11-yn-5-yl]-1,1-diphenylhydrazine
  参考文献：
  名称：

  Novel Radical Cyclization Method Accompanied by Elimination of Hydrazyl Radical

  摘要：

  The potential of hydrazine group as the new radical leaving group was studied. Radical cyclization of (E)-1,1-dialkyl-2-(1-alkyloct-2-en-7-ynyl)hydrazines with n-Bu(3)SnH/AIBN, followed by protodestannylation, gave 1-alkenyl-2-methylenecyclopentanes, which arose by 5-exo cyclization and subsequent beta-elimination of hydrazyl radical.

  DOI：

  10.3987/com-09-s(s)115

文献信息

• Novel Radical Cyclization Method Accompanied by Elimination of Hydrazyl Radical
  作者：Ilhyong Ryu、Shoji Kobayashi、Hidefumi Hirao、Tatsuro Kawauchi

  DOI：10.3987/com-09-s(s)115

  日期：——

  The potential of hydrazine group as the new radical leaving group was studied. Radical cyclization of (E)-1,1-dialkyl-2-(1-alkyloct-2-en-7-ynyl)hydrazines with n-Bu(3)SnH/AIBN, followed by protodestannylation, gave 1-alkenyl-2-methylenecyclopentanes, which arose by 5-exo cyclization and subsequent beta-elimination of hydrazyl radical.