| 1428956-00-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1428956-00-6
• 化学式: C₁₃₅H₁₃₈N₁₈O₆₆
• 分子量: 3068.66
• InChiKey: RVHAFYKKTGALQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.35
• 重原子数：
  219.0
• 可旋转键数：
  81.0
• 环数：
  13.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  1196.55
• 氢给体数：
  12.0
• 氢受体数：
  75.0

反应信息

• 作为产物：
  描述：

  Prop-2-ynyl 4-[[3-[4-[[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoyl]oxymethyl]-3-nitrobenzoyl]oxy-2-[[4-[[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoyl]oxymethyl]-3-nitrobenzoyl]oxymethyl]-2-methylpropanoyl]oxymethyl]-3-nitrobenzoate 、 1,3,5-三(叠氮甲基)苯 在 copper(II) sulfate 、 sodium ascorbate 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 0.33h， 以92%的产率得到
  参考文献：
  名称：

  Synthesis and Degradation of Backbone Photodegradable Polyester Dendrimers

  摘要：

  Dendrimers with fully photodegradable backbones were synthesized through the incorporation of photodegradable o-nitrobenzyl esters into a new dendrimer monomer based on 2,2-bis(hydroxymethyl)propionic acid (bis-MPA). Dendrons were synthesized using a divergent approach, and were subsequently coupled to a core molecule in the final step. Photodegradation was performed and it was demonstrated that the molecules degrade to release bis-MPA. The accessibility of these molecules opens new avenues for the preparation of well-defined, fully photodegradable materials.

  DOI：

  10.1021/ol4004367