1,8-bis(tert-butoxycarbonylamino-imino-methyl)anthracene | 1362737-65-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,8-bis(tert-butoxycarbonylamino-imino-methyl)anthracene
• CAS: 1362737-65-2
• 化学式: C₂₆H₃₀N₄O₄
• 分子量: 462.549
• InChiKey: GEDXFNQOZUAVFC-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  1,8-bis(tert-butoxycarbonylamino-imino-methyl)anthracene 在 盐酸 作用下， 以 乙醚 、 水 为溶剂， 反应 0.25h， 以98%的产率得到1,8-diamidinoanthracene dihydrochloride
  参考文献：
  名称：

  Fluorescent detection of amidinium–carboxylate and amidinium formation using anthracene-based diamidine: an application for the analysis of dicarboxylic acid binding

  摘要：

  An anthracene-based diamidine (1) 'turn-on' fluorescent probe for the detection of dicarboxylic acids has been designed and synthesized. The fluorescence spectra of the diamidine 1 with carboxylic acids that showed two different fluorescence bands, which corresponded to the amidinium-carboxylate (lambda(em)=430-440 nm), and amidinium (lambda(em)=460-470 nm as a broad band) formation, were confirmed by DOSY NMR and TD-DFT calculations. These different fluorescence bands showed the binding mode of carboxylic acids and the stability of formed complexes toward diamidine 1. The fluorescent detection of amidinium carboxylate formation using diamidine 1 was applicable to the detection of alpha,omega-dicarboxylic acids (C-6-C-13) and succeeded in the detection of alpha,omega-dicarboxylic acid (adipic acid) in human urine. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.09.072
• 作为产物：
  描述：

  二碳酸二叔丁酯 、 1,8-diamidinoanthracene dihydrochloride 在 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 1.5h， 以51%的产率得到1,8-bis(tert-butoxycarbonylamino-imino-methyl)anthracene
  参考文献：
  名称：

  Fluorescent detection of amidinium–carboxylate and amidinium formation using anthracene-based diamidine: an application for the analysis of dicarboxylic acid binding

  摘要：

  An anthracene-based diamidine (1) 'turn-on' fluorescent probe for the detection of dicarboxylic acids has been designed and synthesized. The fluorescence spectra of the diamidine 1 with carboxylic acids that showed two different fluorescence bands, which corresponded to the amidinium-carboxylate (lambda(em)=430-440 nm), and amidinium (lambda(em)=460-470 nm as a broad band) formation, were confirmed by DOSY NMR and TD-DFT calculations. These different fluorescence bands showed the binding mode of carboxylic acids and the stability of formed complexes toward diamidine 1. The fluorescent detection of amidinium carboxylate formation using diamidine 1 was applicable to the detection of alpha,omega-dicarboxylic acids (C-6-C-13) and succeeded in the detection of alpha,omega-dicarboxylic acid (adipic acid) in human urine. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.09.072