(E)-1-(dimethoxyphosphoryl)-2-methyl-3-phenylallyl dimethyl phosphate | 1408158-26-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: (E)-1-(dimethoxyphosphoryl)-2-methyl-3-phenylallyl dimethyl phosphate
• 英文别名: [(E)-3-[dimethoxy(oxido)phosphaniumyl]-3-[dimethoxy(oxido)phosphaniumyl]oxy-2-methylprop-1-enyl]benzene
• CAS: 1408158-26-8
• 化学式: C₁₄H₂₂O₇P₂
• 分子量: 364.272
• InChiKey: UCLCOUIFBLMYGB-VAWYXSNFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  23
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  92.3
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  ((E)-2-Methyl-3-phenyl-acryloyl)-phosphonic acid dimethyl ester 在 2-phenyl[1,3,2]dioxaborolane 、 水 、 potassium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 以84%的产率得到(E)-1-(dimethoxyphosphoryl)-2-methyl-3-phenylallyl dimethyl phosphate
  参考文献：
  名称：

  Phenyldioxaborolane promoted synthesis of bisphosphine compounds

  摘要：

  Bisphosphine compounds have a wide range of applications. In this paper, we reported that bisphosphine compounds could be prepared in moderate to good yields from dialkyl acylphosphonates under mild conditions in the presence of phenyldioxaborolane and potassium hydroxide via a C-P bond cleavage and a subsequent 1,2-migration of phosphoryl group. (c) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.09.088

文献信息

• Phenyldioxaborolane promoted synthesis of bisphosphine compounds
  作者：Yin-Wei Sun、Peng-Long Zhu、Qin Xu、Min Shi

  DOI：10.1016/j.tet.2012.09.088

  日期：2012.12

  Bisphosphine compounds have a wide range of applications. In this paper, we reported that bisphosphine compounds could be prepared in moderate to good yields from dialkyl acylphosphonates under mild conditions in the presence of phenyldioxaborolane and potassium hydroxide via a C-P bond cleavage and a subsequent 1,2-migration of phosphoryl group. (c) 2012 Elsevier Ltd. All rights reserved.