[Mn(2-((1)-2-[2-[(1)-2-aza-2-2-(2-hydroxyphenyl)vinyl]phenyl]-1-azavinyl)phenol(-2H))]*H2O | 1181812-93-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [Mn(2-((1)-2-[2-[(1)-2-aza-2-2-(2-hydroxyphenyl)vinyl]phenyl]-1-azavinyl)phenol(-2H))]*H2O
• CAS: 1181812-93-0
• 化学式: C₂₀H₁₄MnN₂O₂*H₂O
• 分子量: 387.297
• InChiKey: VMHOUQRZPUPBLN-FDOBHKDXSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [Mn(2-((1)-2-[2-[(1)-2-aza-2-2-(2-hydroxyphenyl)vinyl]phenyl]-1-azavinyl)phenol(-2H))]*H2O 以 neat (no solvent) 为溶剂， 生成 水合锰
  参考文献：
  名称：

  Spectroscopic study of molecular structures of novel Schiff base derived from o-phthaldehyde and 2-aminophenol and its coordination compounds together with their biological activity

  摘要：

  New Schiff base (H2L) ligand is prepared via condensation of o-phthaldehyde and 2-aminophenol. The metal complexes of Cr(III), Mn(II), Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with the ligand are prepared in good yield from the reaction of the ligand with the corresponding metal salts. They are characterized based on elemental analyses, IR, solid reflectance, magnetic moment, electron spin resonance (ESR), molar conductance, H-1 NMR and thermal analysis (TGA). From the elemental analyses data, the complexes are proposed to have the general formulae [M(L)(H2O)n]center dot yH(2)O (where M = Mn(II) (n = 0,y = 1), Fe(II) (n = y = 0), Co(II) (n = 2,y = 0). Ni(II) (n = y = 2), Cu(II) (n = 0,y = 2) and Zn(II) (n = y = 0), and [MCl(L)(H2O)]center dot yH(2)O (where M = Cr(III) and Fe(III), y = 1-2). The molar conductance data reveal that all the metal chelates are non-electrolytes. IR spectra show that HA is coordinated to the metal ions in a bi-negatively tetradentate manner with ONNO donor sites of the azomethine N and deprotonated phenolic-OH. This is supported by the H-1 NMR and ESR data. From the magnetic and solid reflectance spectra, it is found that the geometrical structures of these complexes are octahedral (Cr(III), Fe(III), Co(H) and Ni(II) complexes), tetrahedral (Mn(II), Fe(II) and Zn(II) complexes) and square planar (Cu(II) complex). The thermal behaviour of these chelates is studied and the activation thermodynamic parameters, such as, E*, Delta H*, Delta S* and Delta G* are calculated from the DrTGA curves using Coats-Redfern method. The parent Schiff base and its eight metal complexes are assayed against two fungal and two bacterial species. With respect to antifungal activity, the parent Schiff base and four metal complexes inhibited the growth of the tested fungi at different rates. Ni(II) complex is the most inhibitory metal complex, followed by Cr(III) complex, parent Schiff base then Co(II) complex. With regard to bacteria, only two of the tested metal complexes (Mn(II) and Fe(II)) weakly inhibit the growth of the two tested bacteria. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2009.04.005
• 作为产物：
  描述：

  salophen 、 水 、 manganese(ll) chloride 以 乙醇 、 水 为溶剂， 以68%的产率得到[Mn(2-((1)-2-[2-[(1)-2-aza-2-2-(2-hydroxyphenyl)vinyl]phenyl]-1-azavinyl)phenol(-2H))]*H2O
  参考文献：
  名称：

  Spectroscopic study of molecular structures of novel Schiff base derived from o-phthaldehyde and 2-aminophenol and its coordination compounds together with their biological activity

  摘要：

  New Schiff base (H2L) ligand is prepared via condensation of o-phthaldehyde and 2-aminophenol. The metal complexes of Cr(III), Mn(II), Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with the ligand are prepared in good yield from the reaction of the ligand with the corresponding metal salts. They are characterized based on elemental analyses, IR, solid reflectance, magnetic moment, electron spin resonance (ESR), molar conductance, H-1 NMR and thermal analysis (TGA). From the elemental analyses data, the complexes are proposed to have the general formulae [M(L)(H2O)n]center dot yH(2)O (where M = Mn(II) (n = 0,y = 1), Fe(II) (n = y = 0), Co(II) (n = 2,y = 0). Ni(II) (n = y = 2), Cu(II) (n = 0,y = 2) and Zn(II) (n = y = 0), and [MCl(L)(H2O)]center dot yH(2)O (where M = Cr(III) and Fe(III), y = 1-2). The molar conductance data reveal that all the metal chelates are non-electrolytes. IR spectra show that HA is coordinated to the metal ions in a bi-negatively tetradentate manner with ONNO donor sites of the azomethine N and deprotonated phenolic-OH. This is supported by the H-1 NMR and ESR data. From the magnetic and solid reflectance spectra, it is found that the geometrical structures of these complexes are octahedral (Cr(III), Fe(III), Co(H) and Ni(II) complexes), tetrahedral (Mn(II), Fe(II) and Zn(II) complexes) and square planar (Cu(II) complex). The thermal behaviour of these chelates is studied and the activation thermodynamic parameters, such as, E*, Delta H*, Delta S* and Delta G* are calculated from the DrTGA curves using Coats-Redfern method. The parent Schiff base and its eight metal complexes are assayed against two fungal and two bacterial species. With respect to antifungal activity, the parent Schiff base and four metal complexes inhibited the growth of the tested fungi at different rates. Ni(II) complex is the most inhibitory metal complex, followed by Cr(III) complex, parent Schiff base then Co(II) complex. With regard to bacteria, only two of the tested metal complexes (Mn(II) and Fe(II)) weakly inhibit the growth of the two tested bacteria. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2009.04.005