N,N-dimethyl-N'-4-hexyloxybenzoylhydrazine | 154372-80-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-dimethyl-N'-4-hexyloxybenzoylhydrazine
• CAS: 154372-80-2
• 化学式: C₁₅H₂₄N₂O₂
• 分子量: 264.368
• InChiKey: ZYBZBLWBZVBJBR-UHFFFAOYSA-N

物化性质

• 密度：
  1.016±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.85
• 重原子数：
  19.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  41.57
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  N,N-dimethyl-N'-4-hexyloxybenzoylhydrazine 在 sodium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 反应 20.0h， 生成 bis(N,N-dimethyl-N'-4-hexyloxybenzoylhydrazomium)-N-hexamethylene aminimide
  参考文献：
  名称：

  Uphill Transport of Metal Picrate through a Liquid Membrane by Ylides

  摘要：

  New pH dependent carrier molecules, aminimides, were synthesized, and their properties were investigated by transport experiments of metal picrate through a liquid membrane. These aminimides have the nitrogen atom bearing a negative charge (ylidic nitrogen atom) and the oxygen atom of the carbonyl group, which interact with metal ions. Since this ylidic nitrogen atom can interact with a proton in solution and be conjugated to the carbonyl group, the extraction equilibrium constant is affected by the substituents of the aminimide and the pH in solution. Thus, the transport rate of metal picrate by the aminimide depended on the substituents and the pH in solution. By using this property of aminimides, a new uphill transport system was constructed and it was found that aminimides are efficient carrier molecules to transport metal picrate against its concentration gradient. The numerical simulation of uphill transport by this pH dependent carrier has been performed by using the improved transport rate equation, and the calculated result is consistent with the experimental result. These results indicate that the uphill transport arises from the difference in the extraction equilibrium constant at the two interfaces between the organic phase and the aqueous phases with different pH values.

  DOI：

  10.1021/j100102a039
• 作为产物：
  描述：

  4-已氧基苯甲酰氯 、 偏二甲肼 在 三乙胺 作用下， 以 苯 为溶剂， 以71.8%的产率得到N,N-dimethyl-N'-4-hexyloxybenzoylhydrazine
  参考文献：
  名称：

  Uphill Transport of Metal Picrate through a Liquid Membrane by Ylides

  摘要：

  New pH dependent carrier molecules, aminimides, were synthesized, and their properties were investigated by transport experiments of metal picrate through a liquid membrane. These aminimides have the nitrogen atom bearing a negative charge (ylidic nitrogen atom) and the oxygen atom of the carbonyl group, which interact with metal ions. Since this ylidic nitrogen atom can interact with a proton in solution and be conjugated to the carbonyl group, the extraction equilibrium constant is affected by the substituents of the aminimide and the pH in solution. Thus, the transport rate of metal picrate by the aminimide depended on the substituents and the pH in solution. By using this property of aminimides, a new uphill transport system was constructed and it was found that aminimides are efficient carrier molecules to transport metal picrate against its concentration gradient. The numerical simulation of uphill transport by this pH dependent carrier has been performed by using the improved transport rate equation, and the calculated result is consistent with the experimental result. These results indicate that the uphill transport arises from the difference in the extraction equilibrium constant at the two interfaces between the organic phase and the aqueous phases with different pH values.

  DOI：

  10.1021/j100102a039

文献信息

• Dealkylation of some hydrazinium salts bearing ω-haloalkyl substituents by diazacrown ethers
  作者：Shinji Tsuchiya、Manabu Senō

  DOI：10.1039/c39930001679

  日期：——

  The reactions of some hydrazinium salts bearing ω-haloalkyl substituents with diazacrown ethers gave the hydrarine derivatives and N-monoalkylated diazacrown ether salts; dealkylation of the hydrazinium salts occurred.

  一些带有 Ï-卤代烷基的肼盐与重氮冠醚反应，生成了水合衍生物和 N-单烷基化的重氮冠醚盐；肼盐发生了脱烷基化反应。