| 82937-63-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 82937-63-1
• 化学式: C₂₄H₂₂N₂O₈
• 分子量: 466.447
• InChiKey: KGEJAGAZLLLNPK-JZZBYWGLSA-N

反应信息

• 作为反应物：
  描述：

  在 间氯过氧苯甲酸 作用下， 以 氯仿 为溶剂， 以2.43 g的产率得到[(1S,2S,4R,6S,7S,9R)-9-[(4-nitrobenzoyl)oxymethyl]-3-oxatricyclo[4.3.0.02,4]nonan-7-yl]methyl 4-nitrobenzoate
  参考文献：
  名称：

  MCPB treatment of (±)-(1α,3α,3aβ,6aβ)-1,2,3,3a,4,6a-hexahydro-1,3-pentalenedimethanol and its O-acyl-protected derivatives; X-ray crystallography

  摘要：

  The treatment of hexahydro-1.3-pentalenedimethanol 1 with MCPB acid gave a pentalenofurane compound 7 instead of an epoxide, in >90% yield by participation of the closer hydroxymethyl group in epoxidation. Acyl-protected derivatives la le gave a mixture of exo- and endo-epoxides 5/6 as expected, with exo-epoxides representing the major compound in all cases. The best yield for exo-epoxide was obtained for diacetate la. Basic hydrolysis of exo-epoxides gave the pentalenofurane compound 7, while that of the endo-epoxide 6c gave the unsubstituted endo-epoxide 6. The structure of the compounds was confirmed by IR, MS, H-1 and C-13 NMR spectra and also by extensive X-ray crystallography of compounds 7c, 7d, 5a, 6c and 7. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2015.04.096