(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine) | 1104003-78-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: (1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine)
• 英文别名: (1R)-1-[10-[(1R)-1-amino-2,2,2-trifluoroethyl]anthracen-9-yl]-2,2,2-trifluoroethanamine
• CAS: 1104003-78-2
• 化学式: C₁₈H₁₄F₆N₂
• 分子量: 372.313
• InChiKey: YXJNKOWIQFQJMV-HZPDHXFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  (Ss,Ss),-N,N'-(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethane-1,1-diyl)bis(2-methylpropane-2-sulfinamide) 在 盐酸 、 甲醇 作用下， 以 1,4-二氧六环 为溶剂， 反应 3.5h， 以70%的产率得到(1R,1'R)-1,1'-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine)
  参考文献：
  名称：

  Preparation of (1R,1′R)-1,1′-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine): a chiral diamine with low basicity

  摘要：

  A new chiral diamine with low basicity was synthesized in enantiopure form. (1R,1'R)-1,1'-(Anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine) was obtained by means of several stereochemically controlled reactions. The structures of the title compound and several intermediates were studied. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.10.082

文献信息

• Preparation of (1R,1′R)-1,1′-(anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine): a chiral diamine with low basicity
  作者：Carla Estivill、Julen Mendizabal、Albert Virgili、Eva Monteagudo、Teresa Flor、Francisco Sánchez-Ferrando、Angel Alvarez-Larena、Juan F. Piniella

  DOI：10.1016/j.tet.2008.10.082

  日期：2009.1

  A new chiral diamine with low basicity was synthesized in enantiopure form. (1R,1'R)-1,1'-(Anthracene-9,10-diyl)bis(2,2,2-trifluoroethanamine) was obtained by means of several stereochemically controlled reactions. The structures of the title compound and several intermediates were studied. (C) 2008 Elsevier Ltd. All rights reserved.