3-diethylaminopropyldiphenylphosphine | 76734-25-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-diethylaminopropyldiphenylphosphine
• 英文别名: Diethylaminopropyl Diphenyl Phosphine；3-diphenylphosphanyl-N,N-diethylpropan-1-amine
• CAS: 76734-25-3
• 化学式: C₁₉H₂₆NP
• 分子量: 299.396
• InChiKey: KXRBUSCGRAZWAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 、 3-diethylaminopropyldiphenylphosphine 、 四苯硼钠 以 乙醇 、 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  具有三脚架四齿配体和双齿“混合”配体的五甲基环戊二烯基铑配合物

  摘要：

  由[Rh 2（C 5 Me 5）2 Cl 4获得的配合物[{Rh（C 5 Me 5）} 3 Cl 5 L] Y [Y = Cl，BF 4或PF 6 ]的合成和性质。]和合适的三脚架四齿配体，即L ＝ N（CH 2 CH 2 PPh 2）3或P（CH 2 CH 2 PPh 2）3。这些单配位体三金属化合物包含两个Rh（C 5 Me 5）Cl 2每个单元都与三脚架配体的末端磷原子和与第三末端磷以及与顶部供体原子相连的Rh（C 5 Me 5）Cl基团结合，N（CH 2 CH 2 PPh 2）3的氮原子为磷对于P（CH 2 CH 2 PPh 2）3。当用氯化四丁基铵处理时，N（CH 2 H 2 PPh 2）3衍生物中的Rh（C 5 Me 5）Cl基团被取代，得到[{Rh（C 5 Me 5）Cl2 } 3 {N（CH 2 CH 2 PPh 2） 3 }]。的位阻因素在取代反应的影响已被合成和表征复合物的[Rh（C研究5我5）氯{R'

  DOI：

  10.1039/dt9820001147
• 作为产物：
  描述：

  N,N-二乙基烯丙胺 、 二苯基膦 、 、 2-Diethylaminopropyl diphenylphosphine 反应 17.0h， 以It was isolated as a clear colorless liquid (Table 3)的产率得到3-diethylaminopropyldiphenylphosphine
  参考文献：
  名称：

  Ligand exchange process for producing alkyl diaryl phosphine rhodium

  摘要：

  披露了在水合甲酰化过程中非常有用的物质组成物。这些组成物是非带电、非螯合的双(烷基二芳基膦)和三(烷基二芳基膦)铑羰基氢化物。烷基基团的取代基包括含有硅烷、硅氧烷、醚、酯、酮和羟基氧、膦氧和磷酸酯磷的杂有机基团、胺、酰胺、胺氧和杂环氮基团。这些组成物是高度稳定和选择性催化剂，在一定条件下用于烯烃的水合甲酰化反应。所披露的催化剂体系含有大量的膦配体，并使用具有高H.sub.2/CO比的α-烯烃和合成气反应物混合物，在相对较低的压力下。它们主要产生由α-烯烃反应物的末端攻击产生的醛。对于低烯烃，例如丁烯-1，可以从保持在高温下并由适当的反应物混合物连续供给的配体反应混合物中优势地连续地去除产物，作为馏分组分。

  公开号：

  US04687866A1

文献信息

• Transition metal complex catalysts
  申请人：Exxon Research and Engineering

  公开号：US04668809A1

  公开（公告）日：1987-05-26

  Compositions of matter are disclosed which are highly useful in hydroformylation processes. The compositions are non-charged, non-chelated bis- and tris-(alkyl diaryl phosphine) rhodium carbonyl hydrides. The substituents of the alkyl group includes heteroorganic radicals containing ether, ester, keto and hydroxy oxygen, phosphine oxide and phosphorus ester phosphorus, amine, amide, amine oxide and heterocyclic nitrogen groups. These compositions are highly stable and selective catalysts for the hydroformylation of olefins under certain conditions. The disclosed catalyst systems contain a large excess of phosphine ligand and employ alpha-olefin plus synthesis gas reactant mixtures having a high H.sub.2 /CO ratio at relatively low pressures. They produce moslty aldehydes derived from terminal attack on the alpha-olefin reactant. In the case of low olefins, such as butene-1, the products can be advantageously removed in a continuous manner, as distillate components from a ligand reaction mixture kept at an elevated temperature and continuously fed by an appropriate mixture of the reactants.

  本发明披露了一种在氢甲酰化过程中非常有用的物质组成物。该组成物是非带电、非螯合的双(烷基二芳基膦)、三(烷基二芳基膦)铑羰基氢化物。烷基基团的取代基包括含有醚、酯、酮和羟基氧、膦氧和磷酸酯磷、胺、酰胺、胺氧和杂环氮基的杂有机基团。这些组成物是高度稳定和选择性的催化剂，可在一定条件下用于烯烃的氢甲酰化反应。披露的催化剂体系含有大量的膦配体，并采用具有高H.sub.2/CO比的α-烯烃加合物和合成气反应物混合物，在相对较低的压力下。它们主要产生从α-烯烃反应物的末端攻击中得到的醛。对于低烯烃，例如丁烯-1，可以从保持在高温下并由适当的反应物混合物连续供给的配体反应混合物中以馏分组分的形式优势地去除产物。
• Selective hydroformylation process using alkyl diaryl phosphine rhodium
  申请人：Exxon Research and Engineering Company

  公开号：US04687874A1

  公开（公告）日：1987-08-18

  Compositions of matter are disclosed which are highly useful in hydroformylation processes. The compositions are non-charged, non-chelated bis- and tris-(alkyl diaryl phosphine) rhodium carbonyl hydrides. The substituents of the alkyl group include heteroorganic radicals containing ether, ester, keto and hydroxy oxygen, phosphine oxide and phosphorus ester phosphorus, amine, amide, amine oxide and heterocyclic nitrogen groups. These compositions are highly stable and selective catalysts for the hydroformylation of olefins under certain conditions. The disclosed catalyst systems contain a large excess of phosphine ligand and employ alpha-olefin plus synthesis gas reactant mixtures having a high H.sub.2 /CO ratio at relatively low pressures. They produce mostly aldehydes derived from terminal attack on the alpha-olefin reactant. In the case of low olefins, such as butene-1, the products can be advantageously removed in a continuous manner, as distillate components from a ligand reaction mixture kept at an elevated temperature and continuously fed by an appropriate mixture of the reactants.

  本发明揭示了一种在加氢甲酰化过程中非常有用的物质组成物。这些组成物是非带电的、非螯合的双(烷基二芳基膦)和三(烷基二芳基膦)钌羰基氢化物。烷基基团的取代基包括含有醚、酯、酮和羟基氧、膦氧和磷酸酯磷、胺、酰胺、胺氧和杂环氮基的杂有机基团。这些组成物是高度稳定和选择性的催化剂，在特定条件下对烯烃的加氢甲酰化反应非常有效。揭示的催化剂系统包含大量过量的膦配体，并使用具有高H.sub.2/CO比的α-烯烃加合物和合成气反应混合物，在相对较低的压力下进行。它们主要产生从α-烯烃反应物的端部攻击中得到的醛类产物。在低烯烃（如丁烯-1）的情况下，可以从保持在升高温度下并通过适当的反应物混合物连续供给的配体反应混合物中作为馏分组分优势地去除产物。
• Heterocycle-substituted alkyl diaryl phosphine rhodium caronyl hydride
  申请人：Exxon Research and Engineering Co.

  公开号：US04595753A1

  公开（公告）日：1986-06-17

  Compositions of matter are disclosed which are highly useful in hydroformylation processes. The compositions are non-charged, non-chelated bis- and tris-(alkyl diaryl phosphine) rhodium carbonyl hydrides. The substituents of the alkyl group include heteroorganic radicals containing silane, silicone, ether, ester, keto and hydroxy oxygen, phosphine oxide and phosphorus ester phosphorus, amine, amide, amine oxide and heterocyclic nitrogen groups. These compositions are highly stable and selective catalysts for the hydroformylation of olefins under certain conditions. The disclosed catalyst systems contain a large excess of phosphine ligand and employ alpha-olefin plus synthesis gas reactant mixtures having a high H.sub.2 /CO ratio at relatively low pressures. They produce mostly aldehydes derived from terminal attack on the alpha-olefin reactant. In the case of low olefins, such as butene-1, the products can be advantageously removed in a continuous manner, as distillate components from a ligand reaction mixture kept at an elevated temperature and continuously fed by an appropriate mixture of the reactants.

  本发明揭示了在羰基化反应中高度有用的物质组成。这些组成物是非带电、非螯合的双和三(烷基二芳基膦)铑羰基氢化物。烷基基团的取代基包括含有硅烷、硅氧烷、醚、酯、酮和羟基氧、膦氧和磷酸酯磷、胺、酰胺、胺氧和杂环氮基的杂有机基团。这些组成物是高度稳定和选择性的催化剂，可在特定条件下用于烯烃的羰基化反应。揭示的催化剂体系含有大量过量的膦配体，并使用具有高H.sub.2/CO比的α-烯烃加合成气反应混合物，在相对较低的压力下进行。它们主要产生从α-烯烃反应物的末端攻击中得到的醛类产物。对于低烯烃，如丁烯-1，可以从保持在升高温度的配体反应混合物中连续地将产物作为馏分组分有利地除去，并通过适当的反应物混合物连续供给。
• Method for producing alkadienols
  申请人：Mitsubishi Chemical Corporation

  公开号：EP0361304A2

  公开（公告）日：1990-04-04

  An improving method for producing alkadienols by reaction of conjugated alkadiene and water in the presence of carbon dioxide and a catalyst composed of a palladium compound and phosphine (or phosphite), wherein the by-products having high boiling point and the palladium catalyst are efficiently separated from the reaction product for re-use without impairing their effectiveness as the catalyst.

  一种通过共轭烷二烯和水在二氧化碳和由钯化合物和膦（或亚磷酸）组成的催化剂存在下反应生产烷二烯醇的改进方法，其中具有高沸点的副产物和钯催化剂可有效地从反应产物中分离出来重新使用，而不会影响其作为催化剂的效果。
• PROCESS FOR PRODUCING ALKADIENOL
  申请人：Mitsubishi Chemical Corporation

  公开号：EP0605735A1

  公开（公告）日：1994-07-13

  A process for producing an alkadienol which comprises reacting a conjugated alkadiene with water in a reaction solvent in the presence of a palladium catalyst, separating the solvent from the resultant reaction mixture by distilling the mixture under the condition wherein the temperature of the bottom oil in a distillation column is 120 °C or below while directly feeding hot water and/or steam as the heat-transfer medium to the column, and subjecting the bottom to phase separation. This process causes neither the decomposition and/or polymerization of the formed alkadienol nor the metallation of the palladium catalyst, and hence serves to inhibit the loss of the alkadienol and the catalyst and provide the objective alkadienol in a high yield.

  一种生产烷二烯醇的工艺，包括在钯催化剂存在下，在反应溶剂中使共轭烷二烯与水反应，在蒸馏塔中底油温度为120℃或以下的条件下，通过蒸馏混合物，将溶剂从生成的反应混合物中分离出来，同时将热水和/或蒸汽作为传热介质直接送入蒸馏塔，并使底部进行相分离。该工艺既不会导致已形成的烷二烯醇分解和/或聚合，也不会导致钯催化剂金属化，因此可抑制烷二烯醇和催化剂的损失，并以高产率提供目标烷二烯醇。