bis(3-tert-butyldiphenylsilyloxybenzyl)ether | 1614826-40-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(3-tert-butyldiphenylsilyloxybenzyl)ether
• 英文别名: Tert-butyl-[3-[[3-[tert-butyl(diphenyl)silyl]oxyphenyl]methoxymethyl]phenoxy]-diphenylsilane；tert-butyl-[3-[[3-[tert-butyl(diphenyl)silyl]oxyphenyl]methoxymethyl]phenoxy]-diphenylsilane
• CAS: 1614826-40-2
• 化学式: C₄₆H₅₀O₃Si₂
• 分子量: 707.072
• InChiKey: QJCCOFUGBDJSGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.28
• 重原子数：
  51
• 可旋转键数：
  14
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-((tert-butyldiphenylsilyl)oxy)benzaldehyde 在 indium(III) triflate 、 三乙基硅烷 作用下， 以 二氯甲烷 为溶剂， 反应 5.0h， 以74%的产率得到bis(3-tert-butyldiphenylsilyloxybenzyl)ether
  参考文献：
  名称：

  Reductive coupling reaction of aldehydes using indium(III) triflate as the catalyst

  摘要：

  A reductive coupling reaction was effectively developed to convert an aldehyde to its symmetrical ether. The successful reactions required Et3SiH and CH2Cl2 as the suitable solvent in the presence of a catalytic amount of In(OTf)(3). Various aldehydes were subjected to the method, and each afforded the expected ethers in good to excellent yields. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.079

文献信息

• Reductive coupling reaction of aldehydes using indium(III) triflate as the catalyst
  作者：Tomoko Mineno、Rie Tsukagoshi、Tsubasa Iijima、Kazuki Watanabe、Hiroyuki Miyashita、Hitoshi Yoshimitsu

  DOI：10.1016/j.tetlet.2014.05.079

  日期：2014.7

  A reductive coupling reaction was effectively developed to convert an aldehyde to its symmetrical ether. The successful reactions required Et3SiH and CH2Cl2 as the suitable solvent in the presence of a catalytic amount of In(OTf)(3). Various aldehydes were subjected to the method, and each afforded the expected ethers in good to excellent yields. (C) 2014 Elsevier Ltd. All rights reserved.