| 1491153-32-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• CAS: 1491153-32-2
• 化学式: C₅₂H₉₀O₃₉S
• 分子量: 1371.33
• InChiKey: VSRYQMUQHHHDNX-JUIYWUAZSA-N

反应信息

• 作为产物：
  描述：

  在 thiopropylagarose 作用下， 反应 2.0h， 生成
  参考文献：
  名称：

  Synthesis of a Thiol-β-cyclodextrin, a Potential Agent for Controlling Enzymatic Browning in Fruits and Vegetables

  摘要：

  A thiol-beta-cyclodextrin was synthesized by a simple and environmentally friendly three-step method comprising epoxy activation of beta-cyclodextrin, thiosulfate-mediated oxirane opening, and further reduction of the S-alkyl thiosulfate to a thiol group. The final step was optimized by using thiopropyl-agarose, a solid phase reducing agent with many advantages over soluble ones. beta-Cyclodextrin thiolation was confirmed by titration with a thiol-reactive reagent, NMR studies, and MALDI-TOF/TOF. Thiolated cyclodextrin had an average value of one thiol group per molecule. Thiol-beta-cyclodextrin proved to be an excellent agent for controlling polyphenol oxidase activity. This copper-containing enzyme is responsible for browning in fruits and vegetables. Under the same conditions, thiol-beta-cyclodextrin generated a reductive microenvironment that increased the antibrowning effect on Red Delicious apples compared to unmodified beta-cyclodextrin.

  DOI：

  10.1021/jf403063s