(2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-octa-6,7-dienoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester | 144027-46-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: (2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-octa-6,7-dienoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester
• CAS: 144027-46-3
• 化学式: C₃₀H₅₀O₄Si
• 分子量: 502.81
• InChiKey: LXQARZUEEGXOAS-BWKNWUBXSA-N

反应信息

• 作为反应物：
  描述：

  (2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-octa-6,7-dienoic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester 在 碘 、 碳酸氢钠 作用下， 以 乙腈 为溶剂， 生成 (R)-2-[(2S,5S)-5-(1-Iodo-vinyl)-tetrahydro-furan-2-yl]-propionic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester 、 (R)-2-[(2S,5R)-5-(1-Iodo-vinyl)-tetrahydro-furan-2-yl]-propionic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester
  参考文献：
  名称：

  Access to -2,5-disubstituted iodovinyltetrahydrofurans via the cyclization of γ-silyloxyallenes using n-iodosuccinimide

  摘要：

  Treatment of gamma-(tert-butyldimethylsiloxy)- or gamma-(trimethylsiloxy)allenes bearing various groups at the ether carbon with N-iodosuccinimide resulted in the formation of iodocyclization products, 1-iodo-1-(tetrahydrofuran-2'-yl)ethenes, in good yields and with high selectivity for the cis diastereomer.

  DOI：

  10.1016/0040-4039(92)88075-g