2-Myristoyl-3-β-D-galactosyl-sn-glycerol | 133174-22-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 2-Myristoyl-3-β-D-galactosyl-sn-glycerol
• 英文别名: [(2R)-1-hydroxy-3-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl] tetradecanoate
• CAS: 133174-22-8
• 化学式: C₂₃H₄₄O₉
• 分子量: 464.597
• InChiKey: LCMZLYJZMRILOF-DTIHPSOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  32
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  146
• 氢给体数：
  5
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  (2'S)-2'-O-(tetradecanoyl)-3'-O-(9Z,12Z,15Z-octadecatrienoyl)-glyceryl-β-D-galactopyranoside 在 boric acid-borax buffer 、 Triton X-100 作用下， 反应 1.0h， 以3.2 mg的产率得到2-Myristoyl-3-β-D-galactosyl-sn-glycerol
  参考文献：
  名称：

  Selective preparation of sn-1 and sn-2 lysogalactolipids by enzymatic hydrolysis using lipase (from Rhizopus arrhizus)

  摘要：

  Selective and quantitative transformations of galactolipids into sn-1 and sn-2 lysogalactolipids by the use of lipase (from Rhizopus arrhizus) were developed.

  DOI：

  10.1016/s0040-4039(00)79660-2

文献信息

• Enzymatic transformation of glyceroglycolipids into sn-1 and sn-2 lysoglyceroglycolipids by use of Rhizopus arrhizus lipase
  作者：Nobutoshi Murakami、Takashi Morimoto、Hideaki Imamura、Akito Nagatsu、Jinsaku Sakakibara

  DOI：10.1016/s0040-4020(01)85063-8

  日期：1994.2

  Lipase from Rhizopus arrhizus catalyzed deacylation of two classes of glyceroglycolipids, monogalactosyl diacylglycerol(MGDG), and digalactosyl diacylglycerol(DGDG), proceeded regiospecifically to furnish sn-1 lysoglyceroglycolipids quantitatively. The lipase also catalyzed complete acyl migration of sn-1 lysoglycerogalacto-lipids leading to sn-2 lysoglycerogalactolipids.
• Selective preparation of sn-1 and sn-2 lysogalactolipids by enzymatic hydrolysis using lipase (from Rhizopus arrhizus)
  作者：Nobutoshi Murakami、Hideaki Imamura、Takashi Morimoto、Taisei Ueda、Shin-ichi Nagai、Jinsaku Sakakibara、Naoki Yamada

  DOI：10.1016/s0040-4039(00)79660-2

  日期：1991.3

  Selective and quantitative transformations of galactolipids into sn-1 and sn-2 lysogalactolipids by the use of lipase (from Rhizopus arrhizus) were developed.