phenyl (2,6-bis(3-((tert-butyldimethylsilyl)oxy)prop-1-en-1-yl)-4-(hydroxymethyl)phenyl)carbamate | 1613259-93-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenyl (2,6-bis(3-((tert-butyldimethylsilyl)oxy)prop-1-en-1-yl)-4-(hydroxymethyl)phenyl)carbamate
• CAS: 1613259-93-0
• 化学式: C₃₂H₄₉NO₅Si₂
• 分子量: 583.916
• InChiKey: COFBRKNZAJYNPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.86
• 重原子数：
  40.0
• 可旋转键数：
  11.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  77.02
• 氢给体数：
  2.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  (4-amino-3,5-bis(3-((tert-butyldimethylsilyl)oxy)prop-1-en-1-yl)phenyl)methanol 、 氯甲酸苯酯 在 碳酸氢钠 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 1.0h， 以74%的产率得到phenyl (2,6-bis(3-((tert-butyldimethylsilyl)oxy)prop-1-en-1-yl)-4-(hydroxymethyl)phenyl)carbamate
  参考文献：
  名称：

  Photo-triggered molecular release based on auto-degradable polymer-containing organic–inorganic hybrids

  摘要：

  The photo-triggered molecular release from the organic-inorganic polymer hybrids is presented in this manuscript. Initially, the preparation of the auto-degradable polymer is explained with the photo-cleavable group at the end of the polymer main-chain. The silica-based dye-loaded hybrids containing these polymers were fabricated. It was found that by UV irradiation, the end capping was removed, and then the auto-degradation occurs through the polymer main-chain. Finally, the molecular release of the loaded dyes was accomplished in various media by the UV irradiation. In particular, it was shown that both of hydrophobic and hydrophilic dyes can be applied in this system. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2014.04.034