butyl 3-(dibenzylamino)propanoate | 1148109-10-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: butyl 3-(dibenzylamino)propanoate
• CAS: 1148109-10-7
• 化学式: C₂₁H₂₇NO₂
• 分子量: 325.451
• InChiKey: AZIYOQKTBQUBRE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.42
• 重原子数：
  24.0
• 可旋转键数：
  10.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  29.54
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  丙烯酸丁酯 、 二苄胺 在 khaya cellulose supported poly(hydroxamic acid) functionalized copper nanoparticles 作用下， 以 甲醇 为溶剂， 反应 5.0h， 以95%的产率得到butyl 3-(dibenzylamino)propanoate
  参考文献：
  名称：

  聚（异羟肟酸）官能化铜催化的C–N键形成反应†

  摘要：

  通过接枝共聚和随后的加氢脱氧过程对khaya纤维素进行表面改性，合成了高活性的聚（异羟肟酸）官能化铜催化剂。FTIR，FESEM，HRTEM，ICP-AES，UV-vis和XPS分析对制备的催化剂进行了很好的表征。在温和的反应条件下，负载型催化剂有效地促进了C–N键的形成反应，并提供了优异的产率。催化剂易于从反应混合物中回收，并且可以重复使用数次，而其催化活性没有任何重大损失。

  DOI：

  10.1039/c6ra08155j

文献信息

• Glycerol as An Efficient Promoting Medium for Organic Reactions
  作者：Yanlong Gu、Joël Barrault、François Jérôme

  DOI：10.1002/adsc.200800328

  日期：2008.9.5

  beneficial effect of water on reaction rate is decreased with an increase of the reactant′s hydrophobicity, we report here that the use of glycerol as solvent was able to considerably accelerate the reaction rate of an organic reaction even starting from more hydrophobic substrates than those usually used on water. Moreover, the possibility of directly using crude glycerol generated by the biodiesel industry

  尽管水对反应速率的有利影响随着反应物疏水性的增加而降低，但我们在此报告，使用甘油作为溶剂能够显着加快有机反应的反应速率，即使是从比疏水底物更多的疏水性底物开始通常在水上使用的那些。此外，在经济和环境上直接使用由生物柴油工业产生的粗制甘油的可能性提高了使用甘油作为溶剂的兴趣。
• Waste corn-cob cellulose supported bio-heterogeneous copper nanoparticles for aza-Michael reactions
  作者：Shaheen M. Sarkar、T. Sultana、Tapan Kumar Biswas、Md. Lutfor Rahman、Mashitah Mohd Yusoff

  DOI：10.1039/c5nj02437d

  日期：——

  Waste corn-cob cellulose supported Cu-nanoparticles were found to be a highly effective catalyst for aza-Michael reactions at room temperature.

  废弃的玉米芯纤维支持的铜纳米颗粒被发现是一种在室温下高效的氮杂Michael反应催化剂。
• Tapioca Cellulose Based Copper Nanoparticles for Chemoselective <i>N</i>-Alkylation
  作者：Md. Shaharul Islam、Bablu Hira Mandal、Tapan Kumar Biswas、Md. Lutfor Rahman、S. S Rashid、Suat-Hian Tan、Shaheen M Sarkar

  DOI：10.1166/jnn.2017.12930

  日期：2017.1.1

  Biomaterials as a support for catalysts are of prime importance. Tapioca root which is an abundant biopolymer source was used to synthesize cellulose supported bio-heterogeneous poly(hydroxamic acid) copper nanoparticles (CuN@PHA) and was characterized by Fourier transform infrared spectroscopy (FTIR), ultraviolet–visible spectroscopy (UV-Vis), field emission scanning electron microscopy (FESEM), X-ray photoelectron spectroscopy (XPS), inductively coupled plasma atomic emission spectroscopy (ICP-AES), transmission electron microscopy (TEM) analyses. The tapioca cellulose supported CuN@PHA (50 mol ppm) effectively catalyzed N-alkylation reaction of aliphatic amines with α,β-unsaturated compounds to give the corresponding alkylated products. High yields up to 95% were achieved for the converted products. The reusability of the cellulose supported nanoparticles was found to be excellent with no significant reduction of its catalytic activity over several cycles. The catalyst showed high catalytic activity having turnover number (TON) 18000 and turnover frequency (TOF) 2250 h−1.

  作为催化剂载体的生物材料至关重要。淀粉作为丰富的生物聚合物来源，被用于合成纤维素负载的生物非均相聚羟肟酸铜纳米颗粒（CuN@PHA），并采用傅里叶变换红外光谱（FTIR）、紫外-可见光谱（UV-Vis）、场发射扫描电子显微镜（FESEM）、X射线光电子光谱（XPS）、电感耦合等离子体原子发射光谱（ICP-AES）、透射电子显微镜（TEM）等手段进行了表征。淀粉纤维素负载的CuN@PHA（50 mol ppm）有效地催化脂肪胺与α,β-不饱和化合物的N-烷基化反应，得到相应的烷基化产物。转化产物的产率高达95%。纤维素负载的纳米颗粒具有优异的重复使用性，在多次循环中其催化活性没有显著降低。该催化剂显示出高催化活性，其转化数（TON）为18000，转化频率（TOF）为2250 h−1。
• [EN] AMINE COMPOUND, REACTIVE COALESCING AGENT, COATING COMPOSITION, COATING LAYER AND RELATED METHODS<br/>[FR] COMPOSÉ AMINE, AGENT COALESCENT RÉACTIF, COMPOSITION DE REVÊTEMENT, COUCHE DE REVÊTEMENT ET PROCÉDÉS ASSOCIÉS
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2021150170A1

  公开（公告）日：2021-07-29

  There is provided a reactive coalescing agent for a coating formulation that is substantially free from volatile organic compounds (VOCs), the coalescing agent comprising one or more amine compounds represented by general formula (I). Also provided are a coating composition, a coating layer, a method of preparing said reactive coalescing agent and a method of preparing said coating layer.

  提供了一种用于涂层配方的反应性聚合剂，该聚合剂基本上不含挥发性有机化合物（VOCs），该聚合剂包括由通式（I）表示的一种或多种胺化合物。还提供了一种涂层组合物、一种涂层层、制备所述反应性聚合剂的方法和制备所述涂层层的方法。
• Palladium-Catalyzed Vinylation of Aminals with Simple Alkenes: A New Strategy To Construct Allylamines
  作者：Yinjun Xie、Jianhua Hu、Yanyu Wang、Chungu Xia、Hanmin Huang

  DOI：10.1021/ja310848x

  日期：2012.12.26

  A novel, highly selective palladium-catalyzed vinylation reaction for the direct synthesis of allylic amines from styrenes and aminals has been established. The utility of this method was also demonstrated by the rapid synthesis of cinnarizine from aldehydes, amines, and simple alkenes in one-pot manner. Mechanistic studies suggested that the reaction proceeds through a valuable cyclometalated Pd(II) complex generated by the oxidative addition of aminal to a Pd(0) species.