diacetylkipukasin E | 1590417-05-2

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 英文名称: diacetylkipukasin E
• CAS: 1590417-05-2
• 化学式: C₂₃H₂₆N₂O₁₁
• 分子量: 506.466
• InChiKey: RTKOHDCJSDEQHA-QYRPDUKASA-N

物化性质

• 密度：
  1.41±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为产物：
  描述：

  kipukasin E 、 乙酸酐 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 6.0h， 以6.9 mg的产率得到diacetylkipukasin E
  参考文献：
  名称：

  Nucleoside derivatives from the marine-derived fungusAspergillusversicolor

  摘要：

  Four nucleoside derivatives (1-4) were isolated from the fungus Aspergillus versicolor derived from the gorgonian Dichotella gemmacea collected in the South China Sea. Their structures were elucidated by comprehensive spectroscopic method of NMR and MS analysis. All isolated metabolites were evaluated for their cytotoxicity, antibacterial activity and lethality towards brine shrimp Artemia salina. Compounds 1/2 exhibited selective antibacterial activity against Staphylococcus epidermidis with an MIC value of 12.5M. It should be noted that 1 and 2, whose structures were listed in SciFinder Scholar, had no associated reference. This is the first report about their isolation, structure elucidation and biological activities.

  DOI：

  10.1080/14786419.2014.891114