2-(1,3-dioxoisoindolin-2-yl)-N-methylpropane-1-sulfinamide | 1380510-50-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-(1,3-dioxoisoindolin-2-yl)-N-methylpropane-1-sulfinamide
• CAS: 1380510-50-8
• 化学式: C₁₂H₁₄N₂O₃S
• 分子量: 266.321
• InChiKey: DIEVRQBZURLRIN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.55
• 重原子数：
  18.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  66.48
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  2-(1,3-dioxoisoindolin-2-yl)-N-methylpropane-1-sulfinamide 在 次氯酸叔丁酯 作用下， 以 乙腈 为溶剂， 反应 0.17h， 生成 2-(1,3-dioxoisoindolin-2-yl)-N-methylpropane-1-sulfonimidoyl chloride
  参考文献：
  名称：

  Novel diamide insecticides: Sulfoximines, sulfonimidamides and other new sulfonimidoyl derivatives

  摘要：

  Novel insecticidal anthranilamides with elaborated sulfur-containing groups are described. The synthesis of compounds with functional groups such as sulfoximines and scarcely reported groups such as sulfonimidoyl hydrazides and hydroxylamides, their in vitro and in vivo biological activity as well as their physical properties are reported. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.03.106
• 作为产物：
  描述：

  2-(1-Sulfanylpropan-2-yl)isoindole-1,3-dione 在 磺酰氯 、 乙酸酐 作用下， 以 二氯甲烷 为溶剂， 生成 2-(1,3-dioxoisoindolin-2-yl)-N-methylpropane-1-sulfinamide
  参考文献：
  名称：

  Novel diamide insecticides: Sulfoximines, sulfonimidamides and other new sulfonimidoyl derivatives

  摘要：

  Novel insecticidal anthranilamides with elaborated sulfur-containing groups are described. The synthesis of compounds with functional groups such as sulfoximines and scarcely reported groups such as sulfonimidoyl hydrazides and hydroxylamides, their in vitro and in vivo biological activity as well as their physical properties are reported. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.03.106