9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene | 179805-19-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene
• 英文别名: 1-(9,10-Dihydroanthracen-9-yl)-2,2-dimethylpropan-1-amine；1-(9,10-dihydroanthracen-9-yl)-2,2-dimethylpropan-1-amine
• CAS: 179805-19-7
• 化学式: C₁₉H₂₃N
• 分子量: 265.398
• InChiKey: QLDDMZBNLOQFES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  三甲基乙腈 在 lithium aluminium tetrahydride 、 正丁基锂 作用下， 以 乙醚 为溶剂， 反应 26.5h， 生成 9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene
  参考文献：
  名称：

  Preparation of enantiomers of 9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene. Conformational study and their behaviour as chiral solvating agents

  摘要：

  Homochiral forms of 9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene were prepared by hydrolysis of crystallised diastereomeric salts of mandelic acid. The activity as chiral solvating agent was tested in the presence of several alcohols and acids. A boat conformation of the central ring was demonstrated by NMR studies and MM3 calculations. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00146-2

文献信息

• Preparation of enantiomers of 9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene. Conformational study and their behaviour as chiral solvating agents
  作者：Adriana Port、Albert Virgili、Carlos Jaime

  DOI：10.1016/0957-4166(96)00146-2

  日期：1996.5

  Homochiral forms of 9-(1-amino-2,2-dimethylpropyl)-9,10-dihydroanthracene were prepared by hydrolysis of crystallised diastereomeric salts of mandelic acid. The activity as chiral solvating agent was tested in the presence of several alcohols and acids. A boat conformation of the central ring was demonstrated by NMR studies and MM3 calculations. Copyright (C) 1996 Elsevier Science Ltd