4-(3,4-dimethoxyphenylmethylene)-2,5-dioxoimidazolidine-1-propionic acid 2-ethylhexyl ester | 113757-49-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(3,4-dimethoxyphenylmethylene)-2,5-dioxoimidazolidine-1-propionic acid 2-ethylhexyl ester
• 英文别名: 2-ethylhexyl 4-(3,4-dimethoxyphenyl)methylene-2,5-dioxo-1-imidazolidinepropionate；Ethylhexyl dimethoxybenzylidene dioxoimidazolidine propionate；2-ethylhexyl 3-[(4E)-4-[(3,4-dimethoxyphenyl)methylidene]-2,5-dioxoimidazolidin-1-yl]propanoate
• CAS: 113757-49-6
• 化学式: C₂₃H₃₂N₂O₆
• 分子量: 432.517
• InChiKey: VTCQGRUUIXLBJY-QGOAFFKASA-N

物化性质

• 密度：
  1.154±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  31
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  94.2
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  (Z)-5-(3,4-dimethoxybenzylidene)imidazolidine-2,4-dione 、 丙烯酸2-乙基己酯 在 氢氧化钾 作用下， 以 N-甲基乙酰胺 、 水 为溶剂， 以77.8%的产率得到4-(3,4-dimethoxyphenylmethylene)-2,5-dioxoimidazolidine-1-propionic acid 2-ethylhexyl ester
  参考文献：
  名称：

  Method of stabilizing a UVB absorbing compound, a stabilized UV

  摘要：

  本发明涉及一种稳定特定UVB吸收化合物的方法，其包括向所述UVB吸收化合物中添加至少一种特定的UVA吸收化合物，其数量为UVB吸收化合物的1份重量基础上的0.1-10份重量。同时，本发明还涉及一种化妆品组合物和一种UV吸收剂，分别包含所述特定的UVB吸收化合物和特定的UVA吸收化合物。

  公开号：

  US05000945A1

文献信息

• Thickener Or Gellant For Oil Materials, Gel Composition Comprising Same, And Method Of Producing Cosmetic Material Or Topical Agent
  申请人：Tamura Seiki

  公开号：US20120328539A1

  公开（公告）日：2012-12-27

  This inventive thickener or gellant for oil materials is characterized by comprising (A) an high molecular weight organopolysiloxane that has a polyglycerol structure-containing hydrophilic group Q and that is represented by the following structural formula (1): R 3-q (R 11 ) q Si—O—(SiR 11 2 —O) n1 —(SiR 11 Q-O) n2 —(SiR 11 L-O) n3 —Si(R) 11 ) q R 3-q wherein R 11 is a monovalent hydrocarbyl group or a hydrogen atom; L is a chain organosiloxane group, n1, n2, and n3 are numbers in the ranges 200≦n1≦1000, 0≦n2≦20, and 0≦n3≦50; R is a group selected from L and Q; q is an integer in the range from 0 to 3; wherein when n2=0, q is an integer in the range from 1 to 3 and at least one R is Q. The thickener or gellant exhibits an excellent compatibility with a variety of oil systems.

  这种用于油料的创新增稠剂或凝胶剂的特点是包含（A）高分子量的有机聚硅氧烷，具有含有聚甘油结构的亲水基团Q，并且由以下结构式（1）表示：R3-q（R11）qSi—O—（SiR112—O）n1—（SiR11Q-O）n2—（SiR11L-O）n3—Si（R）11）qR3-q其中R11是单价的烃基团或氢原子；L是链状有机硅氧烷基团，n1、n2和n3是数字范围在200≦n1≦1000，0≦n2≦20和0≦n3≦50之间；R是从L和Q中选择的一组；q是在0到3的整数范围内；当n2=0时，q是在1到3的整数范围内，并且至少有一个R是Q。该增稠剂或凝胶剂与各种油系统具有良好的相容性。
• NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF
  申请人：ROHTO Pharmaceutical Co., Ltd.

  公开号：US20150065728A1

  公开（公告）日：2015-03-05

  A novel compound which has excellent ultraviolet-absorbing function (especially UVA absorbing function) and excellent hydrophilicity. A benzylidene azolidine derivative represented by structural formula (I) or a salt thereof. In structural formula (I), n represents an integer of 1-5; A 1 represents O, S or N-A 4 ; and each of A 2 , A 3 and A 4 independently represents a hydrogen atom, an alkyl group which may be substituted by a hydroxyl group and has 1-8 carbon atoms, or the like (provided that at least one of A 2 , A 3 and A 4 contains one or more hydroxyl groups). In this connection, when n is an integer of 2-5, the plurality of A 3 O— moieties may be the same as or different.

  一种新型化合物，具有优异的紫外吸收功能（特别是UVA吸收功能）和优异的亲水性。该化合物为结构式（I）所表示的苯甲酰亚氮杂环衍生物或其盐。在结构式（I）中，n表示1-5的整数；A1表示O、S或N-A4；每个A2、A3和A4独立地表示氢原子、烷基（其可以被羟基取代，并具有1-8个碳原子）或类似物（前提是A2、A3和A4中至少有一个含有一个或多个羟基）。在此情况下，当n为2-5的整数时，多个A3O-基团可以相同或不同。
• Silica spheres containing an ultraviolet screen and surface-treated with N-lauroyl-L-lysine powder and cosmetic composition containing them
  申请人：Ajinomoto Co., Inc.

  公开号：EP0679382A1

  公开（公告）日：1995-11-02

  Herein disclosed are cosmetics having spherical silica containing an ultraviolet reflecting material surface-treated with platy N-lauroyl-L-lysine incorporated therein. According to the present invention, those cosmetics having spherical silica containing a conventional ultraviolet reflecting material blended therewith are improved in cosmetic functions such as spreadability upon application, lubricity upon application, smooth feeling on skins, adhesiveness to skins, water repellency, feeling, etc., maintaining the original ultraviolet screening effect.

  本发明公开了一种化妆品，该化妆品具有球形二氧化硅，其中含有一种紫外线反射材料，该紫外线反射材料的表面经过板状 N-月桂酰-L-赖氨酸处理。根据本发明，具有含有传统紫外线反射材料的球形二氧化硅的化妆品在保持原有紫外线屏蔽效果的同时，改善了化妆品的功能，如涂抹时的延展性、涂抹时的润滑性、皮肤上的平滑感、与皮肤的粘附性、防水性、感觉等。
• POWDER COATED WITH SPARINGLY SOLUBLE ULTRAVIOLET ABSORBER
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP0860163A1

  公开（公告）日：1998-08-26

  Powder coated with a sparingly soluble ultraviolet light absorber which is prepared by a method in which the melted sparingly soluble ultraviolet light absorber and an inorganic or organic powder are mixed while heating and then gradually cooled to coat the surface of said powder with the sparingly soluble ultraviolet light absorber, or by a method in which the sparingly soluble ultraviolet light absorber is adsorbed to or made to coat the surface of the inorganic powder or organic powder using a mechanochemical method. The sparingly soluble ultraviolet light absorber can be blended in a high concentration in the system and blended homogeneously in the base agent. Also, stability over time is superior and the ultraviolet light protection effect is high.

  稀溶性紫外线吸收剂涂层粉末，其制备方法是将熔化的稀溶性紫外线吸收剂与无机或有机粉末混合加热，然后逐渐冷却，使稀溶性紫外线吸收剂涂覆在所述粉末的表面，或者使用机械化学方法将稀溶性紫外线吸收剂吸附到无机粉末或有机粉末的表面，或使其涂覆在无机粉末或有机粉末的表面。稀溶性紫外线吸收剂可在体系中以高浓度混合，并均匀地混合在基剂中。此外，长期稳定性优异，紫外线防护效果高。
• SKIN TEXTURE-IMPROVING AGENTS
  申请人：KYOWA HAKKO KOGYO CO., LTD.

  公开号：EP1226809A1

  公开（公告）日：2002-07-31

  The present invention provides a skin-improving agent which comprises, as an active ingredient, proanthocyanidin in which the extent of galloylation per constitutive monomer is 10% or lower (molar ratio).

  本发明提供了一种皮肤改善剂，其有效成分包括原花青素，其中每个构成单体的五倍化程度为 10%或更低（摩尔比）。