N-(2-Guanidinoaethyl)-5-aethyl-5-isopentyl-barbitursaeure | 42074-25-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: N-(2-Guanidinoaethyl)-5-aethyl-5-isopentyl-barbitursaeure
• 英文别名: {2-[5-ethyl-5-(3-methyl-butyl)-2,4,6-trioxo-tetrahydro-pyrimidin-1-yl]-ethyl}-guanidine；2-[2-[5-Ethyl-5-(3-methylbutyl)-2,4,6-trioxo-1,3-diazinan-1-yl]ethyl]guanidine
• CAS: 42074-25-9
• 化学式: C₁₄H₂₅N₅O₃
• 分子量: 311.384
• InChiKey: IYDHWGSAZQXDCM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  131
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• [EN] COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS<br/>[FR] COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DE TROUBLES MÉTABOLIQUES
  申请人：NUSIRT SCIENCES INC

  公开号：WO2018058109A1

  公开（公告）日：2018-03-29

  Methods and compounds useful for reducing, treating, preventing, or sustaining the reduction of a metabolic disease or disorder are provided herein. Also provided herein are compositions and kits for practicing any of the methods described herein.

  本文提供了用于减少、治疗、预防或维持代谢性疾病或紊乱的方法和化合物。本文还提供了用于实施本文中描述的任何方法的组合物和工具包。
• Compositions and methods for treating metabolic disorders
  申请人：NuSirt Sciences, Inc.

  公开号：US10344002B2

  公开（公告）日：2019-07-09

  Methods and compounds useful for reducing, treating, preventing, or sustaining the reduction of a metabolic disease or disorder are provided herein. Also provided herein are compositions and kits for practicing any of the methods described herein.

  本文提供了用于减少、治疗、预防或持续减少代谢性疾病或紊乱的方法和化合物。本文还提供了用于实施本文所述任何方法的组合物和试剂盒。
• COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS
  申请人：NuSirt Sciences, Inc.

  公开号：US20180105498A1

  公开（公告）日：2018-04-19

  Methods and compounds useful for reducing, treating, preventing, or sustaining the reduction of a metabolic disease or disorder are provided herein. Also provided herein are compositions and kits for practicing any of the methods described herein.