4,4',4''-nitrilotribenzohydrazide | 223591-21-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4,4',4''-nitrilotribenzohydrazide
• 英文别名: 4,4',4''-Nitrilotri(benzohydrazide)；4-[4-(hydrazinecarbonyl)-N-[4-(hydrazinecarbonyl)phenyl]anilino]benzohydrazide
• CAS: 223591-21-7
• 化学式: C₂₁H₂₁N₇O₃
• 分子量: 419.443
• InChiKey: SUPWMJHMBDVEHW-UHFFFAOYSA-N

物化性质

• 密度：
  1.383±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  169
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  4,4',4''-nitrilotribenzohydrazide 、 水杨醛 在 溶剂黄146 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成
  参考文献：
  名称：

  An Amide-Containing Metal–Organic Tetrahedron Responding to a Spin-Trapping Reaction in a Fluorescent Enhancement Manner for Biological Imaging of NO in Living Cells

  摘要：

  Metal-organic polyhedra represent a unique class of functional molecular containers that display interesting molecular recognition properties and fascinating reactivity reminiscent of the natural enzymes. By incorporating a triphenylamine moiety as a bright blue emitter, a robust cerium-based tetrahedron was developed as a luminescent detector of nitronyl nitroxide (PTIO), a specific spin-labeling nitric oxide (NO) trapper. The tetrahedron encapsulates molecules of NO and PTIO within the cavity to prompt the spin-trapping reaction and transforms the normal EPR responses into a more sensitively luminescent signaling system with the limit of detection improved to 5 nM. Twelve-fold amide groups are also functionalized within the tetrahedron to modify the hydrophilic/lipophilic environment, ensuring the successful application of biological imaging in living cells.

  DOI：

  10.1021/ja2048489
• 作为产物：
  描述：

  4,4',4''-三苯三甲酸三甲酯 在 一水合肼 作用下， 以 甲醇 为溶剂， 反应 12.0h， 生成 4,4',4''-nitrilotribenzohydrazide
  参考文献：
  名称：

  An Amide-Containing Metal–Organic Tetrahedron Responding to a Spin-Trapping Reaction in a Fluorescent Enhancement Manner for Biological Imaging of NO in Living Cells

  摘要：

  Metal-organic polyhedra represent a unique class of functional molecular containers that display interesting molecular recognition properties and fascinating reactivity reminiscent of the natural enzymes. By incorporating a triphenylamine moiety as a bright blue emitter, a robust cerium-based tetrahedron was developed as a luminescent detector of nitronyl nitroxide (PTIO), a specific spin-labeling nitric oxide (NO) trapper. The tetrahedron encapsulates molecules of NO and PTIO within the cavity to prompt the spin-trapping reaction and transforms the normal EPR responses into a more sensitively luminescent signaling system with the limit of detection improved to 5 nM. Twelve-fold amide groups are also functionalized within the tetrahedron to modify the hydrophilic/lipophilic environment, ensuring the successful application of biological imaging in living cells.

  DOI：

  10.1021/ja2048489

文献信息

• Post‐Nickelation of a Crystalline Trinuclear Copper Organic Framework for Synergistic Photocatalytic Carbon Dioxide Conversion
  作者：Xinxin Wang、Xu Ding、Yucheng Jin、Dongdong Qi、Hailong Wang、Yuesheng Han、Tianyu Wang、Jianzhuang Jiang

  DOI：10.1002/anie.202302808

  日期：——

  A heterometallic framework was fabricated by post-modification of the copper-containing organic framework USTB-11(Cu) with divalent nickel ions. Synergistic effects between trinuclear copper clusters and nickel ions resulted in photocatalytic conversion of CO2 to CO with a high conversion rate and selectivity.

  通过用二价镍离子对含铜有机骨架 USTB-11(Cu) 进行后改性制备异金属骨架。三核铜簇和镍离子之间的协同作用导致CO 2以高转化率和选择性光催化转化为CO。
• Encapsulated Dye in Coordination-Assembled Octahedron for Visible-Light-Driven Proton Reduction and Nitroaromatic Hydrogenation
  作者：Jianxu Li、Jing Wang、Hechuan Li、Xiaoqiong Wen、Cheng He

  DOI：10.1021/acs.inorgchem.4c00505

  日期：2024.5.6

  photosensitizer in the supramolecular metal–organic cage allowed the photoinduced electrons to transfer from the excited state Fl* to the redox cobalt center in a pseudo-intramolecular pathway. The supramolecular system showed good performance in light-driven hydrogen production and the reduction of nitroaromatic compounds. Control experiments based on a mononuclear compound resembling a cobalt corner of the

  为了模仿精细调节的自然光合作用系统，通过使用改性三苯胺配体和氧化还原活性钴离子的一锅自组装合成了大型金属有机八面体。通过将有机染料荧光素（ Fl ）封装在八面体的内腔内，为主客体超分子系统提供了光驱动的氢气生产。超分子金属有机笼中氧化还原位点和光敏剂之间的紧密距离使得光生电子能够以伪分子内途径从激发态Fl*转移到氧化还原钴中心。该超分子系统在光驱动产氢和硝基芳香族化合物的还原方面表现出良好的性能。基于类似于八面体钴角的单核化合物和抑制剂竞争的对照实验提供了类酶催化行为的证据。有限空间内的超分子反应途径有助于主客体系统的优异活性。