1,5-dimethyl-6-oxa-bicyclo[3.2.1]octane | 57238-59-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: 1,5-dimethyl-6-oxa-bicyclo[3.2.1]octane
• 英文别名: 1,5-Dimethyl-6-oxa-bicyclo[3.2.1]octan；1,5-Dimethyl-6-oxabicyclo<3.2.1>octan；6-Oxa-1,5-dimethyl<3.2.1>bicyclooctan；1,5-Dimethyl-6-oxabicyclo[3.2.1]octane
• CAS: 57238-59-2
• 化学式: C₉H₁₆O
• 分子量: 140.225
• InChiKey: TVNRYJLUZVPZHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,5-dimethyl-6-oxabicyclo<3.2.1>octan-7-one 在 吡啶 、 lithium aluminium tetrahydride 、 对甲苯磺酰氯 作用下， 生成 1,5-dimethyl-6-oxa-bicyclo[3.2.1]octane
  参考文献：
  名称：

  CATIONIC DISPLACEMENT OF HYDROGEN BY OXYGEN AT A SATURATED CARBON ATOM

  摘要：

  DOI：

  10.1021/ja01557a056

文献信息

• A New Insertion Reaction of Cationic Oxygen
  作者：Richard A. Sneen、Nina P. Matheny

  DOI：10.1021/ja01072a088

  日期：1964.9
• Fragrance compositions from tertiary terpene alcohols
  申请人：Kane J. Bernard

  公开号：US20070238629A1

  公开（公告）日：2007-10-11

  Cyclic ethers or chloroketones useful as fragrance components or intermediates are made by reacting a saturated, tertiary terpene alcohol with hypochloric acid under conditions effective to promote oxidation. trans-Pinanol gives predominantly 6,9-dimethyl-7-oxatricyclo[4.3.0.0 3.9 ]-nonane, while cis-pinanol yields almost exclusively 1-acetyl-3-(2-chloroethyl)-2,2-dimethylcyclobutane, a new and versatile intermediate for making cyclobutane derivatives having interesting and diverse aromas.
• US7560598B2
  申请人：——

  公开号：US7560598B2

  公开（公告）日：2009-07-14
• [EN] FRAGRANCE COMPOSITIONS FROM TERTIARY TERPENE ALCOHOLS<br/>[FR] COMPOSITIONS DE PARFUM PROVENANT D'ALCOOLS DE TERPENE TERTIAIRES
  申请人：MILLENNIUM SPECIALTY CHEM INC

  公开号：WO2007130218A1

  公开（公告）日：2007-11-15

  [EN] Cyclic ethers or chloroketones useful as fragrance components or intermediates are made by reacting a saturated, tertiary terpene alcohol with hypochloric acid under conditions effective to promote oxidation. trans-Pinanol gives predominantly 6,9-dimethyl-7-oxatricyclo[4.3.0.0^3,9]-nonane, while cis-pinanol yields almost exclusively 1-acetyl-3-(2-chloroethyl)-2,2-dimethyl-cyclobutane, a new and versatile intermediate for making cyclobutane derivatives having interesting and diverse aromas.
  [FR] La présente invention concerne des éthers ou chlorocétones cycliques utiles en tant que composants ou intermédiaires de parfum préparés par la réaction d'un alcool de terpène saturé et tertiaire avec de l'acide hypochlorique dans des conditions efficaces pour favoriser l'oxydation. Le trans-pinanol donne principalement le 6,9-diméthyl-7-oxatricyclo[4.3.0.03⁹]-nonane, tandis que les rendements de cis-pinanol donnent presque exclusivement le 1-acétyl-3-(2-chloroéthyl)-2,2-diméthyl-cyclobutane, un nouvel intermédiaire versatile pour préparer des dérivés cyclobutane ayant des arômes intéressants et divers.
• CATIONIC DISPLACEMENT OF HYDROGEN BY OXYGEN AT A SATURATED CARBON ATOM
  作者：E. J. Corey、R. W. Wiiite

  DOI：10.1021/ja01557a056

  日期：1958.12