(4-(phenylselanyl)phenyl)methanol | 1439200-57-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-(phenylselanyl)phenyl)methanol
• CAS: 1439200-57-3
• 化学式: C₁₃H₁₂OSe
• 分子量: 263.198
• InChiKey: JWBJYEQNOFWUQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.83
• 重原子数：
  15.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  二苯基二硒醚 、 4-羟甲基苯硼酸 在 {Benzil bis[(2-oxidobenzylidene)hydrazone]}copper(II) 作用下， 以 二甲基亚砜 为溶剂， 反应 10.0h， 以70%的产率得到(4-(phenylselanyl)phenyl)methanol
  参考文献：
  名称：

  C-Se cross-coupling of arylboronic acids and diphenyldiselenides over non precious transition metal (Fe, Cu and Ni) complexes

  摘要：

  Various tetradentate and tridentate ligands such as salophane, bishydrazone, bisbenzimidazolyl pyridine and isonicotinohydrazide have been prepared. Transition metal complexes of these ligands with Cu, Ni and Fe have been further synthesized and characterized by UV-vis, IR, NMR and CHN analysis. Catalytic activity of the metal complexes was tested for the cross coupling of diarylchalcogenide with arylboronic acid in DMSO as solvent in presence of a base. These non-precious metal complexes catalysed cross coupling reactions smoothly in shorter reaction time compared to earlier reports with comparable yields.

  DOI：

  10.1016/j.mcat.2018.02.028

文献信息

• Copper-catalyzed C–Se coupling of diphenyl diselenide with arylboronic acids at room temperature
  作者：Bo Zheng、Ying Gong、Hua-Jian Xu

  DOI：10.1016/j.tet.2013.04.124

  日期：2013.7

  An efficient synthetic protocol for the Cu-catalyzed cross-coupling of diphenyl diselenide and arylboronic acid at room temperature was described. This catalytic system could tolerate a variety of arylboronic acids with only 3 mol % amount of CuSO4 as the catalyst and inexpensive 1,10-phen. H2O as the ligand. Moreover, this catalytic system used environment-friendly EtOH as the solvent and catalytic amount of Na2CO3 (20 mol %) as the base in the air. (C) 2013 Elsevier Ltd. All rights reserved.