potassium 3-(3-(1-methyI-1H-benzo[d]imidazole-2-yl)ureido)propanoate | 1233692-45-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: potassium 3-(3-(1-methyI-1H-benzo[d]imidazole-2-yl)ureido)propanoate
• 英文别名: potassium 3-(3-(1-methyl-1H-benzo[d]imidazole-2-yl)ureido)propanoate；Potassium;3-[(1-methylbenzimidazol-2-yl)carbamoylamino]propanoate
• CAS: 1233692-45-9
• 化学式: C₁₂H₁₃N₄O₃*K
• 分子量: 300.359
• InChiKey: HVKAEEOUGVNXGU-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.16
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  99.1
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• BENZOARYLUREIDO COMPOUNDS, AND COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE CONTAINING THE SAME
  申请人：Hahn Hoh-Gyu

  公开号：US20110319456A1

  公开（公告）日：2011-12-29

  Novel benzoarylureido compounds and a use thereof for prevention and/or treatment of the neurodegenerative brain disease are provided. The neurodegenerative brain diseases may include Alzheimer's disease, dementia, Parkinson's disease, stroke, amyloidosis, Pick's disease, Lou Gehrig's disease, Huntington's disease, Creutzfeld-Jakob disease, and the like.

  提供了新型苯甲酰脲类化合物及其用于预防和/或治疗神经退行性脑疾病的用途。神经退行性脑疾病可能包括阿尔茨海默病、痴呆症、帕金森病、中风、淀粉样变性、皮克氏病、路易·格希病、亨廷顿病、克罗伊茨菲尔德-雅各布病等。
• US9012481B2
  申请人：——

  公开号：US9012481B2

  公开（公告）日：2015-04-21
• [EN] BENZOARYLUREIDO COMPOUNDS, AND COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASE CONTAINING THE SAME<br/>[FR] COMPOSÉS BENZOARYLURÉIDO, ET COMPOSITION DESTINÉE AU TRAITEMENT PROPHYLACTIQUE OU THÉRAPEUTIQUE D'UNE MALADIE CÉRÉBRALE NEURODÉGÉNÉRATIVE LES INCLUANT
  申请人：KOREA INST SCI & TECH

  公开号：WO2010077068A2

  公开（公告）日：2010-07-08

  Novel benzoarylureido compounds and a use thereof for prevention and/or treatment of the neurodegenerative brain disease are provided. The neurodegenerative brain diseases may include Alzheimer's disease, dementia, Parkinson's disease, stroke, amyloidosis, Pick's disease, Lou Gehrig's disease, Huntington's disease, Creutzfeld-Jakob disease, and the like.