2-isopropenyl-4,6-dimethylphenol | 1415385-82-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-isopropenyl-4,6-dimethylphenol
• 英文别名: 2,4-Dimethyl-6-prop-1-en-2-ylphenol；2,4-dimethyl-6-prop-1-en-2-ylphenol
• CAS: 1415385-82-8
• 化学式: C₁₁H₁₄O
• 分子量: 162.232
• InChiKey: DDKGBTMZDUBGBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4,6,8-trimethyl-2H-chromen-2-one 在 potassium hydroxide 作用下， 以 乙二醇 为溶剂， 以97%的产率得到2-isopropenyl-4,6-dimethylphenol
  参考文献：
  名称：

  Ethylene glycol as hydrogen donor for the syntheses of thymol analogues via hydrolysis of 4-methylcoumarins

  摘要：

  Treatment of 4-methylcoumarins with potassium hydroxide in ethylene glycol resulted in the formation of the 'normal' 2-isopropenylphenols and/or the 'abnormal' 2-isopropylphenols depending on the nature of the substrates. The solvent ethylene glycol was believed to be the hydrogen donor for double-bonding reduction where 2-isopropylphenol was produced. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.09.122

文献信息

• Ethylene glycol as hydrogen donor for the syntheses of thymol analogues via hydrolysis of 4-methylcoumarins
  作者：Junbiao Chang、Shuyang Wang、Zhenhua Shen、Gang Huang、Yueteng Zhang、Jing Zhao、Changwei Li、Fangfang Fan、Chuanjun Song

  DOI：10.1016/j.tetlet.2012.09.122

  日期：2012.12

  Treatment of 4-methylcoumarins with potassium hydroxide in ethylene glycol resulted in the formation of the 'normal' 2-isopropenylphenols and/or the 'abnormal' 2-isopropylphenols depending on the nature of the substrates. The solvent ethylene glycol was believed to be the hydrogen donor for double-bonding reduction where 2-isopropylphenol was produced. (C) 2012 Elsevier Ltd. All rights reserved.