3-Amino-7-cyclopentyl-4-methyl-heptanoic acid | 849489-44-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-Amino-7-cyclopentyl-4-methyl-heptanoic acid
• 英文别名: 3-Amino-7-cyclopentyl-4-methylheptanoic acid
• CAS: 849489-44-7
• 化学式: C₁₃H₂₅NO₂
• 分子量: 227.347
• InChiKey: UCIBLQOPLARDGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Amino acids with affinity for the alpha-2-delta-protein
  申请人：——

  公开号：US20030195251A1

  公开（公告）日：2003-10-16

  This invention relates to certain &bgr;-amino acids that bind to the alpha-2-delta (&agr;2&dgr;) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.

  这项发明涉及与钙通道的α-2-δ（α2δ）亚基结合的某些β-氨基酸。这些化合物及其药用盐在治疗各种精神疾病、疼痛和其他疾病方面具有用处。
• Amino acids with affinity for the alpha2delta-protein
  申请人：Blazecka Garth Peter

  公开号：US20050101643A1

  公开（公告）日：2005-05-12

  Certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the β-amino acids.

  本发明揭示了结合到钙通道的α2δ亚基的某些β-氨基酸。这些化合物及其药学上可接受的盐在治疗各种精神疾病、疼痛和其他疾病方面非常有用。本发明还揭示了制备β-氨基酸的方法。
• Methods for using amino acids with affinity for the alpha2delta-protein
  申请人：Bramson Candace

  公开号：US20050124669A1

  公开（公告）日：2005-06-09

  This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders.

  本发明涉及一些与钙通道的α2δ亚单位结合的β-氨基酸。这些化合物及其药学上可接受的盐在治疗各种精神疾病、疼痛和其他疾病方面是有用的。
• AMINO ACIDS WITH AFFINITY FOR THE ALPHA-2-DELTA-PROTEIN
  申请人：Blazecka Garth Peter

  公开号：US20070129550A1

  公开（公告）日：2007-06-07

  Certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the β-amino acids.

  本文披露了某些能够与钙通道的α2δ亚单位结合的β-氨基酸。这些化合物及其药用盐在治疗多种精神、疼痛和其他疾病方面具有用途。本文还披露了制备β-氨基酸的方法。
• Amino acids with affinity for the alpha-2-delta protein
  申请人：Warner-Lambert Company LLC

  公开号：EP1614675A2

  公开（公告）日：2006-01-11

  The invention relates to compounds of the formula II, III and IV, compositions comprising them and their use in the treatment of, inter alia, pain.

  本发明涉及式 II、III 和 IV 的化合物、包含这些化合物的组合物以及它们在治疗疼痛等方面的用途。