zinc(II) mandelate | 18984-97-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: zinc(II) mandelate
• 英文别名: ZINC mandelate；zinc;2-hydroxy-2-phenylacetate
• CAS: 18984-97-9；20719-64-6
• 化学式: C₁₆H₁₄O₆Zn
• 分子量: 367.674
• InChiKey: SKBBCPAQJFSAMN-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -1.06
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  121
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  zinc(II) nitrate 、 扁桃酸 以 乙醇 为溶剂， 以>95的产率得到zinc(II) mandelate
  参考文献：
  名称：

  锌（II）促进了2-羟酸酯的水解。羧肽酶A模型

  摘要：

  天然存在的2-羟基酸的Zn（II）配合物已通过两种单独的方法制备：（1）2-羟基酸与Zn（II）的反应；（2）Zn（II）促进的2-羟基酸的酯的水解。例如，在温暖的95％乙醇中0-乙酰基2-羟基十八碳烯酸与Zn（II）的反应导致形成Zn（2-羟基十八碳酸酯）2。该一般反应应提供洞察力，以羧肽酶催化的酯水解中离去基团的金属离子活化的重要性。

  DOI：

  10.1016/0022-1902(80)80069-8

文献信息

• Coating Compositions for Marking Substrates
  申请人：O'Donoghue Karen

  公开号：US20080207444A1

  公开（公告）日：2008-08-28

  The present invention provides coating compositions for marking substrates, which comprise a colour former in an amount of from 0.01 to 50%, a metal salt of a carboxylic acid in an amount of from 0.01 to 50%, a binder in an amount of from 1 to 80% and an organic solvent in an amount of from 1 to 99%, wherein each amount is by weight based on the weight of the composition. The present invention also provides a process for the preparation of the composition of the present invention, substrates coated with these compositions and a process for preparing a marked substrate using these compositions.

  本发明提供了用于标记基底的涂料组合物，其包括以下成分：色发生剂，其含量在0.01%至50%之间；羧酸金属盐，其含量在0.01%至50%之间；粘合剂，其含量在1%至80%之间；有机溶剂，其含量在1%至99%之间。其中，每个含量都是按照组合物的重量计算的。本发明还提供了制备本发明组合物的方法，用这些组合物涂覆的基底以及使用这些组合物制备标记基底的方法。
• Topical Delivery System for Phytosterols
  申请人：GUPTA SHYAM K.

  公开号：US20090042846A1

  公开（公告）日：2009-02-12

  This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof; Wherein, n=0, 1, 2, or 3; and R=H, —CH 2 OH, —CH(OH)—CH 2 OH, —CH(OH)—CH(OH)—CH 2 OH; and R 1 =Substituent selected from a sapogenin, steroid, or terpenoid.

  本发明涉及公式（I）的植物甾醇糖酯，这些酯类适用于局部应用，并用于治疗皮肤状况，包括老年斑、痤疮、细胞抗氧化剂的丧失、胶原蛋白的丧失、皮肤柔韧性的丧失、皮肤柔软性的丧失、皮肤皱纹包括细纹、氧化、辐射损伤、基质金属蛋白酶的功能障碍、酪氨酸酶的功能障碍、自由基的损伤、紫外线的损伤、干燥皮肤、角化病、鱼鳞病、头皮屑、褐色斑点、角化病、黄褐斑、肝斑、色素斑点、眼圈黑色素沉着、皮肤色素沉着包括皮肤变黑、瑕疵、油性皮肤、疣、湿疹、瘙痒性皮肤、银屑病、炎症性皮肤病、局部炎症、角化异常、与衰老相关的皮肤变化、需要清洁剂、调理剂或治疗剂的指甲或皮肤，以及需要洗发水或护发素的头发或头皮，以及其组合；其中，n = 0、1、2或3；R = H、—CH2OH、—CH（OH）—CH2OH、—CH（OH）—CH（OH）—CH2OH；R1 = 从皂甙、类固醇或萜类中选择的取代基。
• Coating compositions for marking substrates
  申请人：Datalase Ltd.

  公开号：US08101544B2

  公开（公告）日：2012-01-24

  The present invention provides coating compositions for marking substrates, which comprise a colour former in an amount of from 0.01 to 50%, a metal salt of a carboxylic acid in an amount of from 0.01 to 50%, a binder in an amount of from 1 to 80% and an organic solvent in an amount of from 1 to 99%, wherein each amount is by weight based on the weight of the composition. The present invention also provides a process for the preparation of the composition of the present invention, substrates coated with these compositions and a process for preparing a marked substrate using these compositions.

  本发明提供了用于标记基材的涂层组合物，其中包括颜料形成剂，其量为0.01至50％，羧酸金属盐，其量为0.01至50％，粘合剂，其量为1至80％和有机溶剂，其量为1至99％，其中每个量均以组合物的重量为基础。本发明还提供了制备本发明组合物的方法，涂有这些组合物的基材和使用这些组合物制备标记基材的方法。
• Additive composition and process for using the same
  申请人：Milliken & Company

  公开号：US10131751B2

  公开（公告）日：2018-11-20

  An additive composition comprises a wax and a nucleating agent. The nucleating agent can be dispersed in the wax. A process for producing a nucleated polymer comprises the steps of (a) providing a reactor; (b) providing an additive composition comprising a wax and a nucleating agent; (c) providing an extruder; (d) reacting in the reactor a reactant mixture comprising an olefin monomer and hydrogen to produce a polyolefin polymer; (e) collecting and recovering the polyolefin polymer produced by the reaction; (f) conveying the polyolefin polymer to the extruder; (g) conveying the additive composition to the extruder; and (g) extruding the polyolefin polymer and the additive composition to produce a nucleated polymer composition.

  添加剂组合物包括蜡和成核剂。成核剂可分散在蜡中。生产成核聚合物的工艺包括以下步骤：(a) 提供反应器；(b) 提供由蜡和成核剂组成的添加剂组合物；(c) 提供挤压机；(d) 在反应器中使由烯烃单体和氢气组成的反应混合物发生反应，生成聚烯烃聚合物；(e) 收集和回收反应生成的聚烯烃聚合物； (f) 将聚烯烃聚合物输送到挤压机； (g) 将添加剂组合物输送到挤压机；以及 (g) 挤压聚烯烃聚合物和添加剂组合物，生成成核聚合物组合物。
• PROCESS FOR THE PREPARATION OF COPOLYESTERS
  申请人：Ferring GmbH

  公开号：EP0986599A2

  公开（公告）日：2000-03-22