trimethyl-[trimethylsilyl-[(4R,7R)-3,8,8-tris[bis(trimethylsilyl)methyl]-2,9-dioxa-3,8-digermatetracyclo[5.5.2.04,13.010,14]tetradeca-1(13),5,10(14),11-tetraen-3-yl]methyl]silane | 582299-89-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: trimethyl-[trimethylsilyl-[(4R,7R)-3,8,8-tris[bis(trimethylsilyl)methyl]-2,9-dioxa-3,8-digermatetracyclo[5.5.2.04,13.010,14]tetradeca-1(13),5,10(14),11-tetraen-3-yl]methyl]silane
• CAS: 582299-89-6
• 化学式: C₃₈H₈₂Ge₂O₂Si₈
• 分子量: 940.932
• InChiKey: KEWZNZNFWYFAQE-LOYHVIPDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.68
• 重原子数：
  50.0
• 可旋转键数：
  12.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  1,4-naphthoquinone etherate 、 bis[bis(trimethylsilyl)methyl]germanium(II) 以 苯 为溶剂， 以3%的产率得到trimethyl-[trimethylsilyl-[(4R,7R)-3,8,8-tris[bis(trimethylsilyl)methyl]-2,9-dioxa-3,8-digermatetracyclo[5.5.2.04,13.010,14]tetradeca-1(13),5,10(14),11-tetraen-3-yl]methyl]silane
  参考文献：
  名称：

  Germylene Reactions with Quinones Shed Light on Germylene Phenone Equilibria

  摘要：

  Ge[CH(SiMe3)(2)](2) (1) and Ge[N(SiMe3)(2)](2) (2) react with anthraquinone and naphthoquinone in a 2:1 ratio to form five-membered rings with the carbonyl oxygens and the ortho carbons of the adjacent aromatic ring. The reaction with 1,4-diacetylbenzene proceeds in a similar fashion with 1; however no reaction is observed with 2. Compounds 1 and 2 react with 1,2-diacetylbenzene to yield a novel bicyclo species. In a previous report describing equilibria between 1 and phenones, it appeared that 2 did not undergo reaction to generate the five-membered ring with the accompanying formation of a conjugated triene. However, these quinone results indicate that an equilibrium can exist between 2 and a phenone moiety. In the reaction with quinones, a second equivalent of germylene effectively traps the conjugated triene by undergoing a 1,4-addition reaction. Unlike the initial triene formation, this second insertion is irreversible.

  DOI：

  10.1021/om0302589