| 916852-37-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• CAS: 916852-37-4
• 化学式: C₂₆H₂₉N₃O₄
• 分子量: 447.534
• InChiKey: NFMSYDLDANXXSI-WAPCQROESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.47
• 重原子数：
  33.0
• 可旋转键数：
  10.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  81.62
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  1,6-二溴己烷 、 4-羟甲基-4'-甲基-2,2'-联吡啶 在 potassium carbonate 、 potassium hydroxide 作用下， 生成
  参考文献：
  名称：

  Ring-Opening Metathesis Polymers for Biodetection and Signal Amplification: Synthesis and Self-Assembly

  摘要：

  The ring-opening metathesis polymerization (ROMP) was used to develop a new class of block copolymers toward biological detection with signal amplification For this, duce classes of ROMP monomers were synthesized. (i) luminescent and electrochemilummescent Ii ansfflon-metal-contaming monomer s, with i uthemum, osmium, and iridium bipyridine units, 0 0 biologically compatible monomers and macromonomers containing oligothylene glycol units, and (m) bioconjugatable monomers as well as monomer s containing the biorecognn ion unit biotin ROMP was used to efficiently combine these monomer s into a mphiphilic di- and triblock copolymers Self-assembly of these block copolymers in aqueous media genermes micellal spherical assemblies, which contain a large number of luminescent transition-metal centels in their col e. a biocompatible and biologically inert protecting shell, and biological recognition units or bioconjuizatable groups on then periphery These micelles can act as luminescent markers for biological molecules with potential for signal amplification In addition, the monomers and polymers reported here can serve is useful biologically enabled building blocks for a number of applications, including drug delivery and tissue engineering

  DOI：

  10.1021/ma100234j

文献信息

• WO2006/130955
  申请人：——

  公开号：——

  公开（公告）日：——