2-Methyl-3-ethoxycarbonyl-2-propenyltriphenylphosphonium Bromide | 33398-38-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Methyl-3-ethoxycarbonyl-2-propenyltriphenylphosphonium Bromide
• 英文别名: 3-carboethoxy-2-methyl-prop-2-enyl triphenylphosphonium bromide；E-3-ethoxycarbonyl-2-methylallyltriphenylphosphonium bromide；(3-Ethoxycarbonyl-2-methylallyl)triphenylphosphonium Bromide；[(E)-4-ethoxy-2-methyl-4-oxobut-2-enyl]-triphenylphosphanium;bromide
• CAS: 33398-38-8
• 化学式: Br*C₂₅H₂₆O₂P
• 分子量: 469.358
• InChiKey: YTCUHHGAWIKMBX-UXJRWBAGSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.49
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-Methyl-3-ethoxycarbonyl-2-propenyltriphenylphosphonium Bromide 在 氢氧化钾 、 lithium aluminium tetrahydride 、 三氯化铝 、 sodium methylate 作用下， 以 甲醇 、 乙醚 为溶剂， 反应 79.0h， 生成 12'-apo-χ-caroten-12'-al
  参考文献：
  名称：

  Sliwka; Nøkleby; Liaaen-Jensen, Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1987, vol. 41, # 4, p. 245 - 252

  摘要：

  DOI：
• 作为产物：
  描述：

  3-甲酰基-2-丁烯酸乙酯 在 吡啶 、 sodium tetrahydroborate 、 三溴化磷 作用下， 以 乙醚 、 乙醇 、 正己烷 、 二氯甲烷 为溶剂， 反应 1.75h， 生成 2-Methyl-3-ethoxycarbonyl-2-propenyltriphenylphosphonium Bromide
  参考文献：
  名称：

  Zhidkova, T. A.; Stashina, G. A.; Bekker, A. R., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, p. 2328 - 2333

  摘要：

  DOI：

文献信息

• A Class of Readily Tunable Planar‐Chiral Cyclopentadienyl Rhodium(III) Catalysts for Asymmetric C–H Activation
  作者：Xiaoqiang Yan、Jijun Jiang、Jun Wang

  DOI：10.1002/anie.202201522

  日期：2022.6.7

  rhodium(III) (CpRhIII) complexes are powerful catalysts for promoting asymmetric C−H activation reactions. At present, their preparations mainly rely on the development of various chiral cyclopentadienyl (Cp) ligands by linking or embedding the Cp motif to or into a certain chiral backbone. In contrast, development of planar-chiral only CpRhIII catalysts bearing non-chiral Cp ligands remains a formidable

  手性半夹心环戊二烯基铑 (III) (CpRh III ) 配合物是促进不对称 C-H 活化反应的强大催化剂。目前，它们的制备主要依赖于通过将Cp基序连接或嵌入到某个手性骨架上来开发各种手性环戊二烯（Cp）配体。相比之下，迄今为止，开发仅具有非手性 Cp 配体的平面手性 CpRh III催化剂仍然是一项艰巨的挑战，并且很大程度上尚未开发。本文描述了一类易于调节的纯平面手性 CpRh III催化剂及其在不对称 C-H 活化反应中的应用。
• Multifunctional Cyclopentadienes as a Scaffold for Combinatorial Bioorganometallics in [(η ⁵ ‐C ₅ H ₂ R ₁ R ₂ R ₃ )M(CO) ₃ ] (M=Re, ^99m Tc) Piano‐Stool Complexes
  作者：Angelo Frei、Bernhard Spingler、Roger Alberto

  DOI：10.1002/chem.201801271

  日期：2018.7.17

  AbstractMultifunctional cyclopentadiene (Cp) ligands and their rhenium and 99mTc complexes were prepared by a versatile synthetic route. The properties of these Cp ligands can be tuned on demand, either during their synthesis (variation of R1) or through post‐synthetic functionalization with two equal or different vectors (V1 and V2). Variation of these groups enables a combinatorial approach in the synthesis of bioorganometallic complexes. This is demonstrated by the preparation of Cp ligands containing both electron‐donating and electron‐withdrawing groups at the R1 position and their subsequent homo‐ or heterofunctionalization with biovector models (benzylamine and phenylalanine) under standard amide bond‐formation conditions. All ligands can be coordinated to the fac‐[Re(CO)3]+ and fac‐[99mTc(CO)3]+ cores to give tetrafunctional complexes in straightforward and functional‐group‐tolerant procedures. The 99mTc complexes were prepared in one step, in 30 min, and under aqueous conditions from generator‐eluted [99mTcO4]−.
• Zhidkova, T. A.; Bekker, A. R.; Vakulova, L. A., Russian Journal of Organic Chemistry, 1984, vol. 20, # 8, p. 1528 - 1532
  作者：Zhidkova, T. A.、Bekker, A. R.、Vakulova, L. A.、Samokhvalov, G. I.

  DOI：——

  日期：——