[2-[(3R,4R)-3,4-dimethoxyphospholan-1-yl]-1-diphenylphosphanylethyl]-diphenylphosphane | 136835-27-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-[(3R,4R)-3,4-dimethoxyphospholan-1-yl]-1-diphenylphosphanylethyl]-diphenylphosphane
• CAS: 136835-27-3
• 化学式: C₃₂H₃₅O₂P₃
• 分子量: 544.55
• InChiKey: HRZLDJSGAVQQCP-CONSDPRKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  37
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,4-dimethoxyphospholane 、 1,1-双(二苯基膦)乙烯 以 四氢呋喃 为溶剂， 反应 16.0h， 以76%的产率得到[2-[(3R,4R)-3,4-dimethoxyphospholan-1-yl]-1-diphenylphosphanylethyl]-diphenylphosphane
  参考文献：
  名称：

  Enantioselektive Katalysen

  摘要：

  The base-catalyzed addition of the optically active P-H phospholanes tarpholane and diopholane to olefins activated by diphenylphosphino or diphenylphosphinoyl groups gives unsymmetrical chelate phosphines which are used as cocatalysts in the hydrogenation of (Z)-alpha-N-acetamidocinnamic acid, in the cross-coupling of 1-phenylethyl Grignard with vinylbromide, and in the hydrosilylation of acetophenone with diphenylsilane.

  DOI：

  10.1016/0022-328x(91)80038-l

文献信息

• Enantioselektive Katalysen
  作者：Henri Brunner、Stephan Limmer

  DOI：10.1016/0022-328x(91)80038-l

  日期：1991.8

  The base-catalyzed addition of the optically active P-H phospholanes tarpholane and diopholane to olefins activated by diphenylphosphino or diphenylphosphinoyl groups gives unsymmetrical chelate phosphines which are used as cocatalysts in the hydrogenation of (Z)-alpha-N-acetamidocinnamic acid, in the cross-coupling of 1-phenylethyl Grignard with vinylbromide, and in the hydrosilylation of acetophenone with diphenylsilane.