1-(3-(6-Oxo-11,12-dihydro-5H-dibenz[b,f]azocin-5-yl)-1-propyl)-3-piperidinecarboxylic acid | 183614-80-4

• 分子结构分类: 有机化合物
• 英文名称: 1-(3-(6-Oxo-11,12-dihydro-5H-dibenz[b,f]azocin-5-yl)-1-propyl)-3-piperidinecarboxylic acid
• 英文别名: 1-[3-(6-Oxo-11,12-dihydrobenzo[c][1]benzazocin-5-yl)propyl]piperidine-3-carboxylic acid
• CAS: 183614-80-4
• 化学式: C₂₄H₂₈N₂O₃
• 分子量: 392.498
• InChiKey: NCYRAWCEPZRCBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  60.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Use of N-substituted azaheterocyclic compounds for the manufacture of a pharmaceutical composition for the treatment of indications related to angiogenesis
  申请人：——

  公开号：US20020045610A1

  公开（公告）日：2002-04-18

  The present invention relates to the use of N-substituted azaheterocyclic compounds or salts thereof, for the treatment of conditions related to angiogenesis.

  本发明涉及使用N-取代的氮杂环化合物或其盐，用于治疗与血管生成有关的疾病。
• N-substituted azaheterocyclic carboxylic acids and alkylesters thereof
  申请人：NOVO NORDISK A/S

  公开号：EP0820450B1

  公开（公告）日：2001-09-12
• USE OF N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INDICATIONS RELATED TO ANGIOGENESIS
  申请人：NOVO NORDISK A/S

  公开号：EP1135129A1

  公开（公告）日：2001-09-26
• [EN] USE OF N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF INDICATIONS RELATED TO ANGIOGENESIS<br/>[FR] UTILISATION DE COMPOSES AZAHETEROCYCLIQUES N-SUBSTITUES POUR LA FABRICATION D'UNE COMPOSITION PHARMACEUTIQUE DESTINEE AU TRAITEMENT D'INDICATIONS SE RAPPORTANT A L'ANGIOGENESE
  申请人：NOVO NORDISK AS

  公开号：WO2000032193A1

  公开（公告）日：2000-06-08

  The present invention relates to the use of N-substituted azaheterocyclic compounds or salts thereof, for the treatment of conditions related to angiogenesis.