1,1-bis(4-carboxyphenyl)bromomethane diethyl ester | 263369-17-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-bis(4-carboxyphenyl)bromomethane diethyl ester
• 英文别名: Ethyl 4-[bromo-(4-ethoxycarbonylphenyl)methyl]benzoate
• CAS: 263369-17-1
• 化学式: C₁₉H₁₉BrO₄
• 分子量: 391.261
• InChiKey: BXRHGQLEUOMNQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,1-bis(4-carboxyphenyl)bromomethane diethyl ester 在 五甲基二乙烯三胺 、 铜 、 copper(I) bromide 作用下， 以 甲苯 为溶剂， 反应 0.5h， 以97%的产率得到1,1,2,2-tetrakis(4-carboxyphenyl)ethane tetraethyl ester
  参考文献：
  名称：

  EP1997798

  摘要：

  公开号：

文献信息

• MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND
  申请人：NIPPON SODA CO., LTD.

  公开号：EP1120391A1

  公开（公告）日：2001-08-01

  Novel molecular compounds containing carboxylic acid derivatives represented by general formula (I) or (II) as the constituent compound and exhibiting excellent performances in various technical fields including selective separation of useful substances, chemical stabilization, nonvolatilization, prolongation of release and powderization, wherein X is (CH2)n or p-phenylene; n is 0, 1, 2 or 3; R1 to R8 and R13 to R20 are each hydrogen, C1-C6 alkyl, C2-C4 alkenyl, phenyl optionally substituted with C1-C6 alkyl, halogeno or C1-C6 alkoxy; and R9 to R12 and R21 to R24 are each hydrogen, C1-C6 alkyl, C2-C4 alkenyl, C7-C12 aralkyl or an alkali metal.

  含有通式(I)或(II)代表的羧酸衍生物作为组成化合物的新型分子化合物，在有用物质的选择性分离、化学稳定、不挥发、延长释放和粉末化等各种技术领域表现出优异性能，其中X为(CH2)n或对亚苯基；n 是 0、1、2 或 3；R1 至 R8 和 R13 至 R20 分别是氢、C1-C6 烷基、C2-C4 烯基、任选被 C1-C6 烷基、卤素或 C1-C6 烷氧基取代的苯基；以及 R9 至 R12 和 R21 至 R24 分别是氢、C1-C6 烷基、C2-C4 烯基、C7-C12 芳基或碱金属。
• Metrod for Producing 1,2-Phenylethane Compound Using Atom Transfer Radical Coupling Reaction
  申请人：Niitani Takeshi

  公开号：US20090275772A1

  公开（公告）日：2009-11-05

  An object of the present invention is to provide a method capable of producing a 1,2-phenylethane compound with extremely high yield in a short amount of time. Disclosed is a method for producing a 1,2-phenylethane compound, which comprises subjecting a compound represented by formula (I): wherein Ra represents a hydrogen atom or a substituted or unsubstituted phenyl group; Rb represents a hydrogen atom or a substituent; n represents an integer of 1 to 5 and, when n is 2 or more, Rb may be the same or different, or may be combined with each other to form a ring; and X represents a halogen atom; to a coupling reaction in the presence of a transition metal complex to produce a compound represented by formula (II):
• US6566548B1
  申请人：——

  公开号：US6566548B1

  公开（公告）日：2003-05-20
• US8034971B2
  申请人：——

  公开号：US8034971B2

  公开（公告）日：2011-10-11