3,5-dimethoxy-4-methylphenethylamine hydrochloride | 4395-23-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,5-dimethoxy-4-methylphenethylamine hydrochloride
• 英文别名: 2-(3,5-Dimethoxy-4-methyl-phenyl)-ethylamine; hydrochloride；Desoxy hydrochloride；2-(3,5-dimethoxy-4-methylphenyl)ethanamine;hydrochloride
• CAS: 4395-23-7
• 化学式: C₁₁H₁₇NO₂*ClH
• 分子量: 231.722
• InChiKey: SKUYSAUJELLSJD-UHFFFAOYSA-N

物化性质

• 熔点：
  244-245 °C

计算性质

• 辛醇/水分配系数(LogP)：
  1.94
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  44.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3,5-dimethoxy-4-methyl-β-nitrostyrene 在 lithium aluminium tetrahydride 、 硫酸 、 盐酸 作用下， 以 四氢呋喃 、 乙醚 、 异丙醇 为溶剂， 以48.3 %的产率得到3,5-dimethoxy-4-methylphenethylamine hydrochloride
  参考文献：
  名称：

  DESOXYSCALINE DERIVATIVES WITH MODIFIED MESCALINE-LIKE ACTION

  摘要：

  A composition of a compound represented by FIG. 1 for use in substance-assisted therapy. A method of changing neurotransmission, by administering a pharmaceutically effective amount of a compound of FIG. 1 to a mammal, interacting with serotonin 5 -HT 2 A receptors in the mammal, in particular also human beings, and inducing psychoactive effects. A method of treating a patient having adverse reactions to psychedelics by administering a desoxyscaline derivative to the patient, and avoiding adverse effects present with psychedelics. A method of changing neurotransmission of an individual, by administering a desoxyscaline derivative, and changing neurotransmission in the individual.

  公开号：

  US20230150906A1