3-Tert-butyl-5-phenylimidazolidine-2,4-dione | 1031685-33-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 3-Tert-butyl-5-phenylimidazolidine-2,4-dione
• CAS: 1031685-33-2
• 化学式: C₁₃H₁₆N₂O₂
• mdl: MFCD12434309
• 分子量: 232.282
• InChiKey: BDQQVKIRKUBQGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.384
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-Tert-butyl-5-phenylimidazolidine-2,4-dione 、 乙酸酐 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以84%的产率得到
  参考文献：
  名称：

  A Cu(I)-Catalyzed C−H α-Amination of Esters. Direct Synthesis of Hydantoins

  摘要：

  This paper describes a novel intermolecular alpha-amination process of esters using CuCl as catalyst and di-tert-butyldiaziridinone as nitrogen source. A variety of hydantoins can be formed effectively under mild reaction conditions.

  DOI：

  10.1021/ja802242h
• 作为产物：
  描述：

  1,3-di-tert-butyl-5-phenylimidazolidine-2,4-dione 在 甲烷磺酸 作用下， 以 正己烷 为溶剂， 反应 10.0h， 以96%的产率得到3-Tert-butyl-5-phenylimidazolidine-2,4-dione
  参考文献：
  名称：

  A Cu(I)-Catalyzed C−H α-Amination of Esters. Direct Synthesis of Hydantoins

  摘要：

  This paper describes a novel intermolecular alpha-amination process of esters using CuCl as catalyst and di-tert-butyldiaziridinone as nitrogen source. A variety of hydantoins can be formed effectively under mild reaction conditions.

  DOI：

  10.1021/ja802242h

文献信息

• INDANE COMPOUNDS AS CCR5 ANTAGONISTS
  申请人：YOUNGMAN Michael

  公开号：US20090187021A1

  公开（公告）日：2009-07-23

  The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

  本发明涉及式（I）的化合物或其药学上可接受的衍生物，用于治疗CCR5相关的疾病和障碍，例如，用于抑制HIV复制，预防或治疗HIV感染，并用于治疗由此导致的获得性免疫缺陷综合症（AIDS）。
• COLORED COMPOSITION, COLORED CURED FILM, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, LIQUID CRYSTAL DISPLAY DEVICE, SOLID-STATE IMAGING DEVICE, AND NOVEL DIPYRROMETHENE METAL COMPLEX COMPOUND OR TAUTOMER THEREOF
  申请人：FUJIFILM CORPORATION

  公开号：US20140038092A1

  公开（公告）日：2014-02-06

  A colored composition including at least one selected from the group consisting of a compound represented by the following formula (I) and a tautomer thereof. In formula (I), R 2 to R 5 each independently represent a hydrogen atom or a monovalent substituent, R 7 represents a hydrogen atom, a halogen atom, an alkyl group, or the like, Ma represents a metal or a metal compound, X 3 and X 4 each independently represent NR, a nitrogen atom, an oxygen atom, or a sulfur atom, R represents a hydrogen atom, an alkyl group, or the like, Y 1 and Y 2 each independently represent NRc, a nitrogen atom, or a carbon atom, Rc represents a hydrogen atom, an alkyl group, or the like, and R 8 and R 9 each independently represent an alkyl group, an alkenyl group, or the like. Z represents an atomic group that forms a nitrogen-containing ring having a specific structure.
• US7531661B2
  申请人：——

  公开号：US7531661B2

  公开（公告）日：2009-05-12
• US7569579B2
  申请人：——

  公开号：US7569579B2

  公开（公告）日：2009-08-04
• US7589204B2
  申请人：——

  公开号：US7589204B2

  公开（公告）日：2009-09-15