monoformylmono-3-hydroxybenzoic acid | 1243461-12-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: monoformylmono-3-hydroxybenzoic acid
• 英文别名: 2-formyl-3-hydroxybenzoic acid；formyl-3-hydroxybenzoic acid
• CAS: 1243461-12-2
• 化学式: C₈H₆O₄
• 分子量: 166.133
• InChiKey: OGHSDOFDWLGWKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 危险性防范说明：
  P261,P264,P271,P280,P302+P352,P304+P340,P305+P351+P338,P312,P362,P403+P233,P501
• 危险性描述：
  H315,H319,H335

反应信息

• 作为反应物：
  描述：

  乙氧甲酰基亚甲基三苯基膦 、 monoformylmono-3-hydroxybenzoic acid 在 N,N-二乙基苯胺 作用下， 反应 1.5h， 生成 2-Oxo-2H-chromene-5-carboxylic acid benzyl ester
  参考文献：
  名称：

  Acaricidal Activity of Tonka Bean Extracts. Synthesis and Structure−Activity Relationships of Bioactive Derivatives

  摘要：

  The acaricidal effects of tonka bean, Dipterix odorata, extracts were investigated on Dermatophagoides pteronyssinus, the European house dust mite, and compared with benzyl benzoate as a standard acaricidal compound. A cyclohexane extract was the most effective, with an EC50 = 0.075 g/m(2) after a 24 h period, as compared with benzyl benzoate (0.025 g/m(2)). Bioassay-guided fractionation of this extract led to the isolation of coumarin (1). Pharmacomodulation of this compound led us to test 20 analogues (2-21), which were either synthesized or purchased.

  DOI：

  10.1021/np020563j
• 作为产物：
  描述：

  乌洛托品 、 间羟基苯甲酸 在 三氟乙酸 作用下， 反应 6.0h， 生成 monoformylmono-3-hydroxybenzoic acid
  参考文献：
  名称：

  Acaricidal Activity of Tonka Bean Extracts. Synthesis and Structure−Activity Relationships of Bioactive Derivatives

  摘要：

  The acaricidal effects of tonka bean, Dipterix odorata, extracts were investigated on Dermatophagoides pteronyssinus, the European house dust mite, and compared with benzyl benzoate as a standard acaricidal compound. A cyclohexane extract was the most effective, with an EC50 = 0.075 g/m(2) after a 24 h period, as compared with benzyl benzoate (0.025 g/m(2)). Bioassay-guided fractionation of this extract led to the isolation of coumarin (1). Pharmacomodulation of this compound led us to test 20 analogues (2-21), which were either synthesized or purchased.

  DOI：

  10.1021/np020563j

文献信息

• CYCLIC COMPOUND, PRODUCTION PROCESS THEREOF, RADIATION-SENSITIVE COMPOSITION AND RESIST PATTERN FORMATION METHOD
  申请人：Takasuka Masaaki

  公开号：US20120282546A1

  公开（公告）日：2012-11-08

  Disclosed are: a cyclic compound which has high solubility in a safe solvent, is highly sensitive, enables the formation of a resist pattern having a good shape, and rarely causes resist pattern collapse; a process for producing the cyclic compound; a radiation-sensitive composition containing the cyclic compound; and a resist pattern formation method using the composition. Specifically disclosed are: a cyclic compound having a specific structure; a process for producing the cyclic compound; a radiation-sensitive composition containing the compound; and a resist pattern formation method using the composition.

  本发明涉及一种具有高溶解度、高灵敏度、能够形成良好形状的抗蚀图案，且很少引起抗蚀图案崩塌的环状化合物；一种制备该环状化合物的方法；一种含有该环状化合物的辐射敏感组合物；以及使用该组合物的抗蚀图案形成方法。具体揭示了一种具有特定结构的环状化合物，制备该环状化合物的方法，含有该化合物的辐射敏感组合物以及使用该组合物的抗蚀图案形成方法。
• Fuel oils
  申请人：Sutkowski C. Andrew

  公开号：US20060059770A1

  公开（公告）日：2006-03-23

  The use of an additive composition to improve the conductivity of a fuel oil. The additive composition comprises a polymeric condensation product formed by the reaction of an aliphatic aldehyde or ketone, or a reactive equivalent, with at least one ester of p-hydroxybenzoic acid.

  使用一种添加剂组合物来提高燃油的导电性。该添加剂组合物包含一种聚合物缩合产物，该聚合物缩合产物由脂肪族醛或酮或活性等同物与至少一种对羟基苯甲酸酯反应形成。
• CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：EP2505576B1

  公开（公告）日：2019-04-24
• Fuel additives comprising a colloidal metal compound.
  申请人：Infineum International Limited

  公开号：EP1612256B1

  公开（公告）日：2012-06-13
• Additives for fuel oils
  申请人：Infineum International Limited

  公开号：EP2230226B1

  公开（公告）日：2017-01-18