2-phenyl-3,3-bis(2,4,6-trimethylphenyl)spiro[4aH-1,2,3-benzodiazagermine-4,9'-fluorene] | 132775-02-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: 2-phenyl-3,3-bis(2,4,6-trimethylphenyl)spiro[4aH-1,2,3-benzodiazagermine-4,9'-fluorene]
• CAS: 132775-02-1
• 化学式: C₄₃H₄₀GeN₂
• 分子量: 657.394
• InChiKey: ZDZOLTGWVVJADZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.72
• 重原子数：
  46.0
• 可旋转键数：
  3.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  15.6
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2-phenyl-3,3-bis(2,4,6-trimethylphenyl)spiro[4aH-1,2,3-benzodiazagermine-4,9'-fluorene] 以 乙醚 为溶剂， 生成 ((CH₃)3C₆H₂)2Ge(CC₁₂H₈)(N(C₆H₅)NHC₆H₄)
  参考文献：
  名称：

  二聚芴基亚烷基与不饱和氮化合物的反应性

  摘要：

  Dimesitylfluorenylidenegermane (1) reacts with ethylbenzylideneamine (PhCH = NEt) to give, according to a [2 + 2] cycloaddition, the very thermally stable four-membered-ring germaazetidine 2. In contrast, imines with a NH function, such as (diphenylmethylidene)amine (Ph2C = NH), react only as protic reagents. A [2 + 4] cycloaddition is observed with azobenzene, affording 5, which slowly aromatizes to 6 or thermally rearranges to give the [2 + 2] cycloadduct germadiazetidine 7. In the case of nitrosobenzene, only the germanone dimer 17 and imine 9 have been observed, probably via the preliminary formation of transient four-membered heterocycle 15.

  DOI：

  10.1021/om00050a054
• 作为产物：
  描述：

  (mesityl)2Ge(fluorenylidene) 、 偶氮苯 以 乙醚 、 苯 为溶剂， 以58%的产率得到2-phenyl-3,3-bis(2,4,6-trimethylphenyl)spiro[4aH-1,2,3-benzodiazagermine-4,9'-fluorene]
  参考文献：
  名称：

  二聚芴基亚烷基与不饱和氮化合物的反应性

  摘要：

  Dimesitylfluorenylidenegermane (1) reacts with ethylbenzylideneamine (PhCH = NEt) to give, according to a [2 + 2] cycloaddition, the very thermally stable four-membered-ring germaazetidine 2. In contrast, imines with a NH function, such as (diphenylmethylidene)amine (Ph2C = NH), react only as protic reagents. A [2 + 4] cycloaddition is observed with azobenzene, affording 5, which slowly aromatizes to 6 or thermally rearranges to give the [2 + 2] cycloadduct germadiazetidine 7. In the case of nitrosobenzene, only the germanone dimer 17 and imine 9 have been observed, probably via the preliminary formation of transient four-membered heterocycle 15.

  DOI：

  10.1021/om00050a054