[Cu(1,2-bis((2-phenyl-2-(pyridine-2-yl)hydrozono)methyl)benzene)(ClO4)][ClO4] | 1353053-47-0

• 分子结构分类: 有机化合物
• 英文名称: [Cu(1,2-bis((2-phenyl-2-(pyridine-2-yl)hydrozono)methyl)benzene)(ClO4)][ClO4]
• 英文别名: [Cu(Timpy)(ClO4)][ClO4]
• CAS: 1353053-47-0
• 化学式: C₃₀H₂₄ClCuN₆O₄*ClO₄
• 分子量: 731.008
• InChiKey: JGQBONZOIFMMOS-JMLBDHGPSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  copper(II) perchlorate hexahydrate 、 1,2-bis((E)-(2-phenyl-2-(pyridine-2-yl)hydrazono)methyl)benzene 以 二氯甲烷 为溶剂， 生成 [Cu(1,2-bis((2-phenyl-2-(pyridine-2-yl)hydrozono)methyl)benzene)(ClO4)][ClO4]
  参考文献：
  名称：

  Self-activated DNA cleavage and nitric oxide reactivity studies on mononuclear copper complexes derived from tetradentate ligands

  摘要：

  Two new tetradentate ligands Timpy (1,2-bis((E)-(2-phenyl-2-(pyridine-2-yl)hydrozono)methyl)benzene) and Gimpy ((1Z,2Z)-1,2-bis(2-phenyl-2-(pyridine-2-yl)hydrozono)ethane) were synthesized and characterized. Mononuclear complexes [Cu(Timpy)(ClO4)](ClO4) (1) and [Cu(Gimpy)](ClO4)(2) (2) were synthesized and characterized by IR, UV-visible and conductivity measurements. The molecular structure of [Cu(Timpy)(ClO4)] (ClO4) (1) was determined by single crystal X-ray diffraction and structural index parameter (T=0.4725) supported distorted square planar geometry at the metal centre. Electrochemical studies for 1 and 2 were investigated. Two-fold applications of these complexes were examined. First, self-activated DNA cleavage activity of complexes 1 and 2 and mechanism of nuclease activity. Second, the complexes were utilized as fluorescence probe for the detection of nitric oxide in solution. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2011.09.038