ethyl 3-methyl-5-phenyl-pyridazine-4-carboxylate | 1233823-88-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: ethyl 3-methyl-5-phenyl-pyridazine-4-carboxylate
• CAS: 1233823-88-5
• 化学式: C₁₄H₁₄N₂O₂
• 分子量: 242.277
• InChiKey: QPMYPTVMSIFDHH-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  3-methyl-5-phenyl-2,5-dihydro-pyridazine-4-carboxylic acid ethyl ester 在 盐酸 作用下， 以 氯仿 为溶剂， 反应 240.0h， 生成 ethyl 3-methyl-5-phenyl-pyridazine-4-carboxylate
  参考文献：
  名称：

  Organocatalyzed synthesis of chiral non-racemic 1,4-dihydropyridazines

  摘要：

  Chiral non-racemic 1,4-dihydropyridazines were prepared by the reaction of 1,2-diaza-1,3-dienes with arylacetaldehydes under organocatalytic conditions. L-Proline and (S)-(+)-1-(2-pyrrolidinylmethyl)pyrrolidine coupled with trifluoroacetic acid were used as organocatalysts. Enantiomeric excesses ranged from 25% to 78%. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.03.007