1,3-bis(2,6-diisopropyl)-4,5-dihydro-1H-imidazolinium trifluoromethanesulfonate | 1309583-11-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3-bis(2,6-diisopropyl)-4,5-dihydro-1H-imidazolinium trifluoromethanesulfonate
• 英文别名: 1,3-bis(2,6-diisopropylphenyl)imidazolinium trifluoromethanesulfonate
• CAS: 1309583-11-6
• 化学式: CF₃O₃S*C₂₇H₃₉N₂
• 分子量: 540.69
• InChiKey: LCNRAYGNTSRSDF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  7.42
• 重原子数：
  37.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  63.45
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  2,6-二异丙基苯胺 在 溶剂黄146 、 N,N-二异丙基乙胺 作用下， 以 乙腈 为溶剂， 反应 16.5h， 生成 1,3-bis(2,6-diisopropyl)-4,5-dihydro-1H-imidazolinium trifluoromethanesulfonate
  参考文献：
  名称：

  An Efficient Synthesis of Imidazolinium Salts Using Vinyl Sulfonium Salts

  摘要：

  The synthesis of imidazolinium salts from the reaction of formamidines and (2-bromoethyl)diphenylsulfonium triflate is described. A variety of symmetrical and unsymmetrical imidazolinium Inflate salts were synthesized in high yield in short reaction times under mild conditions. Aromatic and aliphatic N-substituents work well. The reaction is proposed to proceed via generation of a vinyl sulfonium salt Intermediate frorr the bromoethylsulfonium triflate.

  DOI：

  10.1021/ol2009472

文献信息

• Preparation of imidazolinium salts by the Pd-catalyzed reduction of thioureas with triethylsilane and trialkylsilyl triflate
  作者：Takehiko Matsumura、Masahisa Nakada

  DOI：10.1016/j.tetlet.2014.01.022

  日期：2014.2

  A Pd-catalyzed method for the preparation of imidazolinium salts from the corresponding thioureas that could then be used for the synthesis of imidazolium and amidinium salts is described. This method has great potential because all the required reagents are readily available and thioureas are safely converted to their corresponding precursors of NHCs under mild conditions.

  描述了由相应的硫脲制备咪唑啉鎓盐的Pd催化方法，该方法随后可用于合成咪唑鎓盐和idi鎓盐。该方法具有巨大的潜力，因为所有所需的试剂都易于获得，并且硫脲在温和的条件下可以安全地转化为其相应的NHCs前体。