8,9-dimethyl-1,9-dihydro-purine-6-thione | 69341-04-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: 8,9-dimethyl-1,9-dihydro-purine-6-thione
• 英文别名: 8,9-Dimethyl-1,9-dihydro-purin-6-thion；8,9-dimethyl-3H-purine-6-thione
• CAS: 69341-04-4
• 化学式: C₇H₈N₄S
• 分子量: 180.233
• InChiKey: WRLPQFBXZXVGGM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  74.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-amino-1,2-dimethyl-1H-imidazole-4-carbothioic acid amide 在 乙酸酐 作用下， 生成 8,9-dimethyl-1,9-dihydro-purine-6-thione
  参考文献：
  名称：

  Synthesis of monosulfated saccharides in the spacered form

  摘要：

  The sulfated (Su) saccharides 3-Su-Galbeta, 3-Su-GaINAcbeta, 4-Su-GalNAcbeta, 6-Su-GalNAcalpha, 6-Su-GlcNAcbeta, 6-Su-LacNAcbeta, 6'-Su-LacNAcbeta, 3'-Su-Galbeta1-3GlcNAcbeta and 3'-Su-Galbeta1-3GalNAcalpha, all monosaccharides in D-configuration, have been synthesised in the form of 3-aminopropyl or 3-trifluoroacetamidopropyl glycosides.

  DOI：

  10.1070/mc2002v012n06abeh001652

文献信息

• Analogs of nitrobenzylthioinosine
  申请人：Ijzermann Pieter Adriaan

  公开号：US20070197528A1

  公开（公告）日：2007-08-23

  Analogs or derivatives of nitrobenzylthioinosine, pharmaceutical compositions comprising such analogs or derivatives, and the use of such analogs or derivatives of nitrobenzylthioinosine for the treatment of pain and various other diseases.
• Synthesis of monosulfated saccharides in the spacered form
  作者：Tatyana V. Ovchinnikova、Ekaterina V. Shipova、Marina A. Sablina、Galina V. Pazynina、Inna S. Popova、Aleksandr B. Tuzikov、Nicolai V. Bovin

  DOI：10.1070/mc2002v012n06abeh001652

  日期：2002.1

  The sulfated (Su) saccharides 3-Su-Galbeta, 3-Su-GaINAcbeta, 4-Su-GalNAcbeta, 6-Su-GalNAcalpha, 6-Su-GlcNAcbeta, 6-Su-LacNAcbeta, 6'-Su-LacNAcbeta, 3'-Su-Galbeta1-3GlcNAcbeta and 3'-Su-Galbeta1-3GalNAcalpha, all monosaccharides in D-configuration, have been synthesised in the form of 3-aminopropyl or 3-trifluoroacetamidopropyl glycosides.