| 1251950-71-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1251950-71-6
• 化学式: C₂₁H₁₈O₂
• 分子量: 302.373
• InChiKey: BKYQYDJCAYJPQH-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 丙二酸二甲酯 在 1,1'-双(二苯基膦)二茂铁 、 N,O-双三甲硅基乙酰胺 、 bis(η3-allyl-μ-chloropalladium(II)) 、 potassium acetate 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 生成 dimethyl 2-[1-(naphthalen-1-yl)-3-phenylallyl]malonate 、 dimethyl 2-[3-(naphthalen-1-yl)-1-phenylallyl]malonate
  参考文献：
  名称：

  Asymmetric allylic substitutions on symmetrical and non-symmetrical substrates using [5]ferrocenophane ligands

  摘要：

  A series of [5]ferrocenophane diphosphane ligands were used in Pd-catalyzed allylic substitution reactions. With a symmetrical substrate, 1,3-diphenylpropenyl acetate, enantioselectivities between 70% and 94% ee were observed. Several non-symmetrically substituted allylic substrates were also used. Depending on the substituents of the non-symmetrical allylic substrates, various degrees of regioselectivity (from 1:1 to 100:0) and enantioselectivity (from 0% to 96% ee) were observed. Tentative catalytically active complexes were studied by DFT computational methods. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2010.05.054