octadecyltriphenylphosphonium iodide | 32339-45-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: octadecyltriphenylphosphonium iodide
• 英文别名: C18PI；Triphenyl(octadecyl)phosphonium iodide；octadecyl(triphenyl)phosphanium;iodide
• CAS: 32339-45-0
• 化学式: C₃₆H₅₂P*I
• 分子量: 642.687
• InChiKey: UPTNBQLYGFZKLB-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  7.25
• 重原子数：
  38
• 可旋转键数：
  20
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  octadecyltriphenylphosphonium iodide 在 hexafluorophosphoric acid 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 24.0h， 以90%的产率得到octadecyltriphenylphosphonium hexafluorophosphate
  参考文献：
  名称：

  Ionic liquids: structuration agents in a fluorinated matrix

  摘要：

  首次成功证明了在氟化基质中使用基于吡啶、咪唑和磷鎓阳离子的离子液体作为功能性构建块，从而实现将纳米级结构与所得到的离聚物的优异机械性能相结合的材料。

  DOI：

  10.1039/c0cc04273k
• 作为产物：
  描述：

  1-碘十八烷 、 三苯基膦 以 甲苯 为溶剂， 反应 24.0h， 以97%的产率得到octadecyltriphenylphosphonium iodide
  参考文献：
  名称：

  Ionic liquids: structuration agents in a fluorinated matrix

  摘要：

  首次成功证明了在氟化基质中使用基于吡啶、咪唑和磷鎓阳离子的离子液体作为功能性构建块，从而实现将纳米级结构与所得到的离聚物的优异机械性能相结合的材料。

  DOI：

  10.1039/c0cc04273k

文献信息

• Synthesis of long-chain fatty acid derivatives as a novel anti-Alzheimer’s agent
  作者：Hong-Yan Zhang、Yu-ichiro Yamakawa、Yuji Matsuya、Naoki Toyooka、Chihiro Tohda、Suresh Awale、Feng Li、Shigetoshi Kadota、Yasuhiro Tezuka

  DOI：10.1016/j.bmcl.2013.12.008

  日期：2014.1

  In order to develop new drugs for Alzheimer's disease, we prepared 17 fatty acid derivatives with different chain lengths and different numbers and positions of double bonds by using Wittig reaction and stereospecific hydrogenation of triple bonds as key reactions. Among them, (4Z,15Z)-octadecadienoic acid (10) and (23Z,34Z)-heptatriacontadienoic acid (16) showed the most potent neurite outgrowth activities on A beta(25-35)-treated rat cortical neurons, which activities were comparable to that of a positive control, NGF. Both fatty acids 10 and 16 possess two (Z)-double bonds at the n-3 and n-14 positions, which might be important for the neurite outgrowth activity. (C) 2013 Elsevier Ltd. All rights reserved.
• Nanostructuration of ionic liquids in fluorinated matrix: Influence on the mechanical properties
  作者：Sébastien Livi、Jannick Duchet-Rumeau、Jean-François Gérard

  DOI：10.1016/j.polymer.2011.01.052

  日期：2011.3

  In this work, a new method to prepare fluorinated coatings with mechanical properties enhanced has been developed. Pyridinium, imidazolium, and phosphonium ionic liquids have been synthesized and used as new synthetic building blocks in a polytetrafluoroethylene matrix. The strategy demonstrated using long alkyl chain cations provides an opportunity to prepare nanomaterials with a nanoscale structuration. The design of these new ionic and nanostructured materials is very dependent on the cation anion combination of ILs. The morphology analyzed by transmission electronic microscopy (TEM) shows that it is clearly tuned by the chemical nature of ILs. The finest structuration leads to a dramatic compromise between stiffness and deformation of material. The small-angle X-Ray scattering (SAXS) shows the evolution of the ionic networks during the mechanical sollicitation. (C) 2011 Elsevier Ltd. All rights reserved.