diphenylsulfene | 72422-34-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diphenylsulfene
• 英文别名: (Phenyl-sulfonylmethyl)benzene；[phenyl(sulfonyl)methyl]benzene
• CAS: 72422-34-5
• 化学式: C₁₃H₁₀O₂S
• 分子量: 230.287
• InChiKey: BODPXFWUQDOOLE-UHFFFAOYSA-N

物化性质

• 密度：
  1.20±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  35.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  diphenylsulfene 以 gaseous matrix 为溶剂， 生成 3,3-Diphenyloxathiirane 2-oxide
  参考文献：
  名称：

  Matrix Isolation of Diphenylsulfene and Diphenyl-α-sultine

  摘要：

  Diphenylsulfene (5) and diphenyl-alpha-sultine 6 were generated in cryogenic matrices by three independent routes: (i) the thermal reaction of diphenylcarbene (8) and SO2, (ii) the photochemically induced hetero Wolff rearrangement of sulfonylcarbene 11, and (iii) oxygen transfer from ozone to diphenylsulfine 16. Isotopic labeling with C-13 and O-18 allows for the assignment of several characteristic IR vibrations of 5. Irradiation with lambda > 375 nm results in the rearrangement of 5 to 6, which is the first alpha-sultine that has been characterized spectroscopically. The final Product on UV irradiation of 6 is benzophenone (9) and sulfur monoxide.

  DOI：

  10.1021/ja962949k
• 作为产物：
  描述：

  [苯基(亚磺酰基)甲基]苯 以 gaseous matrix 为溶剂， 生成 diphenylsulfene
  参考文献：
  名称：

  Matrix Isolation of Diphenylsulfene and Diphenyl-α-sultine

  摘要：

  Diphenylsulfene (5) and diphenyl-alpha-sultine 6 were generated in cryogenic matrices by three independent routes: (i) the thermal reaction of diphenylcarbene (8) and SO2, (ii) the photochemically induced hetero Wolff rearrangement of sulfonylcarbene 11, and (iii) oxygen transfer from ozone to diphenylsulfine 16. Isotopic labeling with C-13 and O-18 allows for the assignment of several characteristic IR vibrations of 5. Irradiation with lambda > 375 nm results in the rearrangement of 5 to 6, which is the first alpha-sultine that has been characterized spectroscopically. The final Product on UV irradiation of 6 is benzophenone (9) and sulfur monoxide.

  DOI：

  10.1021/ja962949k

文献信息

• [EN] TARGETED COVALENT PROBES AND INHIBITORS OF PROTEINS CONTAINING REDOX-SENSITIVE CYSTEINES<br/>[FR] SONDES COVALENTES CIBLÉES ET INHIBITEURS DE PROTÉINES CONTENANT DES CYSTÉINES SENSIBLES À L'OXYDORÉDUCTION
  申请人：SCRIPPS RESEARCH INST

  公开号：WO2014089546A1

  公开（公告）日：2014-06-12

  Covalent, irreversible small-molecule inhibitors that modify the sulfenyl form (i.e., sulfenic acid, RSOH and sulfenamide, RSNR'2) of therapeutically important proteins (particularly kinases and phosphatases) are disclosed, where the compositions include a compound having a substituted aryl or heterocyclic core structure that promotes binding interactions with a specific protein, and a nucleophilic reaction center (carbon, nitrogen, sulfur, or phosphorous) that is capable of forming a covalent bond with a sulfenic acid- or sulfenamide-modified cysteine residue in the protein. Methods for synthesizing these compounds are also disclosed, as well as methods of using them for determining the bioactivity of a chemical composition comprising an active compound toward a specific protein and for determining the potency of an inhibitor against a specific protein.

  揭示了用于修饰治疗重要蛋白质（特别是激酶和磷酸酶）的亚硫酰形式（即亚硫酸，RSOH和亚硫酰胺，RSNR'2）的共价、不可逆的小分子抑制剂，其中组合物包括具有取代芳基或杂环核结构的化合物，促进与特定蛋白质的结合相互作用，以及能够与蛋白质中的亚硫酸或亚硫酰胺修饰的半胱氨酸残基形成共价键的亲核反应中心（碳、氮、硫或磷）。还揭示了合成这些化合物的方法，以及使用它们确定包含活性化合物的化学组合物对特定蛋白质的生物活性以及确定抑制剂对特定蛋白质的效力的方法。
• METHOD OF MANUFACTURING BIPYRIDINIUM COMPOUND AND SYNTHETIC INTERMEDIATE OF THE SAME, METHOD OF MANUFACTURING DYE COMPOUND, AND NOVEL BIPYRIDINIUM COMPOUND AND NOVEL DYE COMPOUND COMPRISING THE SAME
  申请人：Nii Kazumi

  公开号：US20090082570A1

  公开（公告）日：2009-03-26

  Provided is a method of manufacturing a bipyridinium compound denoted by general formula (A). In general formula (A), Ar 1 and Ar 2 each independently denote an optionally substituted (hetero)aryl group, R 3 and R 4 each independently denote a substituent that may form a ring with a pyridine ring to which the substituent substitutes, m3 and m4 each independently denote an integer ranging from 0 to 4, X denotes a halogen atom or RSO 3 , and R denotes an optionally substituted aryl group or alkyl group. The method can manufacture a 4,4′-bipyridinium compound under mild reaction conditions in an integrated manner without separation of intermediates.

  提供了一种制造双吡啶化合物的方法，其通用式为(A)。在通用式(A)中，Ar1和Ar2分别独立表示可选择取代的(杂)芳基团，R3和R4分别独立表示可与取代基形成环的基团，m3和m4分别独立表示范围从0到4的整数，X表示卤原子或RSO3，R表示可选择取代的芳基团或烷基团。该方法可以在温和的反应条件下以一体化方式制造4,4'-双吡啶化合物，无需中间体的分离。
• Resin useful for resist, resist composition and pattern forming process using the same
  申请人：KABUSHIKI KAISHA TOSHIBA

  公开号：US20020098441A1

  公开（公告）日：2002-07-25

  According to the present invention, a resist resin having in its structure a specific bridged-bond-containing aliphatic ring, and a resist composition comprising the same are provided. By using this resist composition, a resist pattern excellent in both transparency against short-wavelength light and dry-etching resistance can be formed by alkali development with high resolution.

  根据本发明，提供了一种在其结构中具有特定桥式键含有的脂环的抗蚀树脂，以及包括该树脂的抗蚀组合物。通过使用这种抗蚀组合物，可以通过高分辨率的碱性显影形成对短波长光具有优异透明度和干法刻蚀抗性的抗蚀图案。
• Liquid ink and recording apparatus
  申请人：Toshiba Tec Kabushiki Kaisha

  公开号：EP1357159A2

  公开（公告）日：2003-10-29

  There is disclosed a liquid ink comprising a photo acid generating agent that generates an acid upon irradiation with light, a coloring component, and at least one kind of a solvent that is polymerized in the presence of an acid. It is preferable that the amount of the photo acid generating agent contained in the liquid ink falls within a range of between 1 part by weight and 10 parts by weight relative to 100 parts by weight of the solvent, the coloring component consists of a pigment, and the solvent contains at least 50 parts by weight of an acid polymerizable compound, the acid polymerizing compound polymerizing in the presence of the acid, having an alicyclic skeleton and/or an aliphatic skeleton having a viscosity of 50 mPa·s or less and a boiling point of 150°C or more under room temperature and atmospheric pressure.

  本发明公开了一种液体油墨，该油墨由在光照射下产生酸的光酸生成剂、着色成分和至少一种在酸存在下聚合的溶剂组成。相对于 100 重量份的溶剂，液体油墨中所含的光酸生成剂的量最好在 1 重量份到 10 重量份之间，着色成分由颜料组成、溶剂中含有至少 50 份（重量）的可酸聚合化合物，该酸聚合化合物在酸存在下聚合，具有脂环族骨架和/或脂肪族骨架，在室温和常压下粘度为 50 mPa-s 或更低，沸点为 150°C 或更高。
• Ink for ink jet and ink jet recording apparatus
  申请人：Toshiba Tec Kabushiki Kaisha

  公开号：EP1514911A1

  公开（公告）日：2005-03-16

  There is disclosed an ink jet recording apparatus (1) comprising a color ink container (5) having a capacity V1 accommodating therein a solvent polymerizable in the presence of an acid and a colorant, a reaction liquid container (3) having a capacity V2 (V2

  本发明公开了一种喷墨记录装置 (1)，包括一个容量为 V1 的彩色墨水容器 (5)，其中装有可在酸和着色剂存在下聚合的溶剂；一个容量为 V2 (V2水输送到记录头的供应管。