碘酚兰 | 4430-24-4

• 物质功能分类: 生物化工 - 生化试剂 - 生物染料
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 中文名称: 碘酚兰
• 中文别名: 3,3',5,5',-四碘苯酚砜基酚酞；四碘酚磺酞；3",3",5",5"-四碘苯酚磺酞
• 英文名称: iodophenol red
• 英文别名: 3,3-bis-(4-hydroxy-3,5-diiodo-phenyl)-3H-benz[c][1,2]oxathiol-1,1-dioxide；3,3-Bis-(4-hydroxy-3,5-dijod-phenyl)-3H-benz[c][1,2]oxathiol-1,1-dioxid；3',3'',5',5''-tetraiodophenolsulfone-phthalein；4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis[2,6-diiodophenol] S,S-dioxide；Iodophenol blue；4-[3-(4-hydroxy-3,5-diiodophenyl)-1,1-dioxo-2,1λ6-benzoxathiol-3-yl]-2,6-diiodophenol
• CAS: 4430-24-4
• 化学式: C₁₉H₁₀I₄O₅S
• 分子量: 857.969
• InChiKey: RXNYILISXGUYFG-UHFFFAOYSA-N

物化性质

• 熔点：
  229 °C (dec.)(lit.)
• 沸点：
  615.3±55.0 °C(Predicted)
• 密度：
  2.615±0.06 g/cm3(Predicted)
• 溶解度：
  微溶于水；溶于乙醇、甲醇、丙酮、乙醚、乙酸
• 最大波长(λmax)：
  433nm
• 稳定性/保质期：

  在常温常压下稳定，红黑色小结晶或红色粉末。它溶于水、乙醇和氢氧化钠溶液，同时也溶于乙酸乙酯。

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  29
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  92.2
• 氢给体数：
  2
• 氢受体数：
  5

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  2934991000

制备方法与用途

制备方法：

• 酸碱指示剂，pH3.0（黄色）～4.8（蓝色）
• 吸附指示剂

合成制备方法： 酸碱指示剂，pH3.0（黄色）～4.8（蓝色）。吸附指示剂。

用途简介： 暂无相关信息。

文献信息

• Copolycarbonates of phenolphthalein polycarbonates and other polycarbonates and their preparation
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0013282A1

  公开（公告）日：1980-07-23

  This invention is directed to a copolycarbonate of a polycarbonate of a trityldiol such as phenolphthalein and a polycarbonate of another diol such as bisphenol-A and to a process for preparing the copolycarbonate. The copolycarbonate is prepared by contacting the starting polycarbonates under conditions of shear and/or temperature sufficient to cause reaction of the polycarbonates to form a copolycarbonate of the polycarbonates. The copolycarbonates of this invention exhibit generally improved impact resistance, clarity and flame resistance as compared with the starting polycarbonates.

  本发明涉及一种三元二醇（如酚酞）聚碳酸酯与另一种二元醇（如双酚 A）聚碳酸酯的共聚碳酸酯，以及制备该共聚碳酸酯的工艺。共聚碳酸酯的制备方法是：在剪切力和/或温度足以使聚碳酸酯发生反应形成聚碳酸酯的共聚碳酸酯的条件下，使起始聚碳酸酯接触。与起始聚碳酸酯相比，本发明的共聚碳酸酯通常具有更好的抗冲击性、透明度和阻燃性。
• Methods for coating surfaces with antimicrobial agents
  申请人：The Board of Regents of the University of Texas System

  公开号：US10589003B2

  公开（公告）日：2020-03-17

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.

  本发明公开了用抗菌剂涂覆或浸渍表面的方法，包括用包括抗菌剂和溶剂的组合物接触表面，并通过加热固化表面。还公开了降低需要使用医疗器械的受试者发生或恶化感染风险的方法，包括用抗菌剂涂覆或浸渍医疗器械表面，然后通过加热固化表面，从而降低发生或恶化感染的风险。
• Tracer reagents that enhance reaction-product analysis
  申请人：Ward W. Brian

  公开号：US20050148009A1

  公开（公告）日：2005-07-07

  A composition suitable for formulation of an enzymatic reaction mixture, the composition comprising a reaction component essential for an ex-vivo non-polymerase enzymatic reaction in which a substrate is catalyzed by an enzyme in a reaction mixture to form a product, and a tracer compatible with the enzyme, the composition being substantially free of the substrate.

  一种适用于配制酶促反应混合物的组合物，该组合物包括体内外非聚合酶酶促反应所必需的反应组分（在该反应中，底物在反应混合物中被酶催化形成产物）和与酶相容的示踪剂，该组合物基本上不含底物。
• Method of detecting viable cells
  申请人：Mizutani Takaaki

  公开号：US20060040400A1

  公开（公告）日：2006-02-23

  A method of detecting and quantifying viable cells in a sample. The method includes fluorescently staining the cells by adding a fluorescent dye into the sample or putting the sample in contact with the fluorescent dye. A quenching dye is then added to the stained sample, or the sample is put into contact with the quenching dye, at a pH different from the pH in the viable cells. The quenching dye used is permeable through the membrane of a viable cell and does not readily absorb fluorescence of the fluorescent dye at the pH in the viable cells, but absorbs the fluorescence of the fluorescent dye at the pH of the fluorescent dye. Next, the sample, now stained with the fluorescent dye and the quenching dye, is illuminated by an excitation light for the fluorescent dye at a pH different from the pH in the viable cells and the fluorescence emitted from the sample is collected and detected.

  一种检测和量化样品中存活细胞的方法。该方法包括向样品中加入荧光染料或使样品与荧光染料接触，对细胞进行荧光染色。然后在染色样品中加入淬灭染料，或让样品与淬灭染料接触，淬灭染料的 pH 值与存活细胞的 pH 值不同。所使用的淬灭染料可透过存活细胞的膜，在存活细胞的 pH 值下不易吸收荧光染料的荧光，但在荧光染料的 pH 值下会吸收荧光染料的荧光。接下来，用荧光染料和淬灭染料对样品进行染色，用荧光染料的激发光照射样品，激发光的 pH 值不同于有活力细胞的 pH 值，收集并检测样品发出的荧光。
• Methods for coating and impregnating medical devices with antiseptic compositions
  申请人：Raad Issam

  公开号：US20050197634A1

  公开（公告）日：2005-09-08

  The present invention provides methods of coating or impregnating medical devices with an antiseptic composition that will inhibit or prevent the nosocomial infections typically associated with the use of such medical devices. The present invention further provides methods of coating or impregnating medical devices that produce devices with effective activity against infection, while avoiding destroying the devices or causing the devices to become toxic. In addition, the invention provides medical devices coated or impregnated with antiseptic compositions by the aforementioned novel methods.

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