(PhCH(C3H5)O)2SiHPh | 1425941-74-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (PhCH(C3H5)O)2SiHPh
• 英文别名: (PhCH(C₃H₅)O)₂SiHPh
• CAS: 1425941-74-7；1454318-49-0；1454318-51-4
• 化学式: C₂₆H₂₈O₂Si
• 分子量: 400.593
• InChiKey: XHKIJSQKCWVZKN-UHFFFAOYSA-N

物化性质

• 沸点：
  479.0±38.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.45
• 重原子数：
  29.0
• 可旋转键数：
  9.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  苯基环丙基甲酮 、 苯硅烷 在 MnN(salen-3,5-tBu2) 作用下， 以 氘代乙腈 为溶剂， 反应 2.0h， 以21%的产率得到环丙基苯基碳酸酯
  参考文献：
  名称：

  An Efficient Catalyst Based on Manganese Salen for Hydrosilylation of Carbonyl Compounds

  摘要：

  A manganese salen complex is shown to be an effective (pre)catalyst in the hydrosilylation of aldehydes and ketones. The present system features an earth-abundant and inexpensive base metal, low catalyst loading, and functional group tolerance. Mechanistic studies suggest that the reaction likely proceeds through a reduced manganese(III) hydride species that undergoes electrophilic attack by the carbonyl substrates.

  DOI：

  10.1021/om400805v

文献信息

• Scope and Mechanistic Studies of Catalytic Hydrosilylation with a High-Valent Nitridoruthenium(VI)
  作者：Srinivas Abbina、Shi Bian、Casey Oian、Guodong Du

  DOI：10.1021/cs300848h

  日期：2013.4.5

  Hydrosilylation catalyzed by a high-valent nitridonithenium(VI) compound, [RuN(saldach)(CH3OH)(+)[ClO4](-) (1, where saldach is the dianion of racemic N,N'-cyclohexan-diyl-bis(salicylideneimine)) is described. Using phenylsilane as reductant, a variety of unsaturated organic substrates, including aldehydes, ketones, and imines, are effectively reduced to alcohols and amines, respectively, accompanied by the redistribution of PhSiH3 at silicon. Mechanistic studies indicate that the catalysis proceeds via silane activation rather than carbonyl activation, and the silane is likely activated via multiple pathways, including a radical-based pathway.