(E)-(3,4-dibromobut-3-en-1-yl)benzene | 1325203-55-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-(3,4-dibromobut-3-en-1-yl)benzene
• 英文别名: (E)-(3,4-dibromobut-3-enyl)benzene；[(E)-3,4-dibromobut-3-enyl]benzene
• CAS: 1325203-55-1
• 化学式: C₁₀H₁₀Br₂
• 分子量: 289.997
• InChiKey: NADFQDNTTFZKLH-CSKARUKUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  4-苯基-1-丁炔 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以67%的产率得到(E)-(3,4-dibromobut-3-en-1-yl)benzene
  参考文献：
  名称：

  Selective 1,2-dihalogenation and oxy-1,1-dihalogenation of alkynes by N-halosuccinimides

  摘要：

  1,2-Dihalogenation and oxy-1,1-dihalogenation of alkynes by N-halosuccinimides can be selectively realized through using different reaction conditions. alpha,beta-Dihalo alkenes were obtained exclusively using THF as solvent without using any catalyst, while alpha,alpha-dihalo ketones were synthesized using a mixed solvent of THF and H2O in the presence of FeCl3 center dot 6H(2)O. Terminal aromatic alkynes are smoothly transformed into alpha,alpha-dihalo ketones on water without a catalyst. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.06.047

文献信息

• 10.1021/acs.orglett.4c01778
  作者：Singh, Harshvardhan、Hewa Inaththappulige, Supuni I.N.、Tak, Raj K.、Giri, Ramesh

  DOI：10.1021/acs.orglett.4c01778

  日期：——

  dibromination of unactivated alkenes and alkynes has been demonstrated by using methyl α-bromoacetate as a mild brominating agent. A near-visible light (370 nm) light-emitting diode (LED) mediates this simple dibromination reaction under mild conditions with the inexpensive and nontoxic α-bromoacetate. The reaction proceeds well with both terminal and internal alkenes and alkynes and those contained

  通过使用 α-溴乙酸甲酯作为温和的溴化剂，已证明光诱导未活化的烯烃和炔烃的邻位二溴化。近可见光 (370 nm) 发光二极管 (LED) 在温和条件下利用廉价且无毒的 α-溴乙酸盐介导这种简单的二溴化反应。该反应对于末端和内部的烯烃和炔烃以及N/O-杂环中所含的烯烃和炔烃均进行良好，表明其在合成二溴化有机化合物中的多功能性。
• Selective 1,2-dihalogenation and oxy-1,1-dihalogenation of alkynes by N-halosuccinimides
  作者：Jinhua Liu、Wenjuan Li、Chao Wang、Yao Li、Zhiping Li

  DOI：10.1016/j.tetlet.2011.06.047

  日期：2011.8

  1,2-Dihalogenation and oxy-1,1-dihalogenation of alkynes by N-halosuccinimides can be selectively realized through using different reaction conditions. alpha,beta-Dihalo alkenes were obtained exclusively using THF as solvent without using any catalyst, while alpha,alpha-dihalo ketones were synthesized using a mixed solvent of THF and H2O in the presence of FeCl3 center dot 6H(2)O. Terminal aromatic alkynes are smoothly transformed into alpha,alpha-dihalo ketones on water without a catalyst. (C) 2011 Elsevier Ltd. All rights reserved.