[Ag(2-methylimidazole)₂(9-anthracenecarboxylate)] | 1438416-93-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: [Ag(2-methylimidazole)₂(9-anthracenecarboxylate)]
• 英文别名: [Ag(2-Me-imH)₂(9-aca)]
• CAS: 1438416-93-3
• 化学式: C₂₃H₂₁AgN₄O₂
• 分子量: 493.314
• InChiKey: NHQOQSMNDWBRGV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  2-甲基咪唑 、 [Ag₂(9-aca)₂] 以 乙腈 为溶剂， 以51%的产率得到[Ag(2-methylimidazole)₂(9-anthracenecarboxylate)]
  参考文献：
  名称：

  Synthesis, structure and biological activity of silver(I) complexes of substituted imidazoles

  摘要：

  [Ag-2(9-aca)(2)] (9-acaH = 9-anthracenecarboxylic acid) interacts with DMSO and a selection of substituted imidazoles giving [Ag-4(DMSO)(4)(9-aca)(4)] (1), [Ag(2-Me-imH)(2)(9-aca)] (2), [Ag(4-Ph-imH)(2)(9-aca)] (3), [Ag(2-Mebenz-imH)2(()9-aca)] (4), [Ag(2-Mebenz-im)] (6), [Ag(Benz-im)] (7), [Ag(2-Ph-im)] (8) and [Ag(4,5-CN-im)] (9) (2-Me-imH = 2-methylimidazole; 4-Ph-imH = 4-phenylimidazole; 2-Mebenz-imH = 2-methylbenzimidazole; Benz-imH = benzimidazole; 2-Ph-imH = 2-phenylbenzimidazole; 4,5-CN-imH = 4,5-dicyanoimidazole). In the carboxylate/imidazole complexes 2-4, the imidazole ligand is in the neutral form, whilst in complexes 6-9 the imidazolate ligand is deprotonated and no carboxylate ligand is present. Attempted recrystallization of 4 from EtOH gives the metal-free, imidazolium salt, 2-Mebenz-imH(2))(9-aca)center dot H2O (5). The X-ray crystal structures of complexes 1 and 2 and the salt 5 were determined. Antimicrobial screening showed that the Ag(l) complexes were substantially more active against the fungus Candida albicans than the bacterial species, methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli. Some of the complexes offer a good prognosis for Galleria mellonella (larvae of the greater wax moth) infected with a lethal dose of C. albicans cells. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2013.03.057