| 1394252-25-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• CAS: 1394252-25-5
• 化学式: C₁₅H₁₂N₄O₂
• 分子量: 280.286
• InChiKey: CLBJTWUATXBXBL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.89
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.54
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  zinc(II) acetate dihydrate 、 在 sodium acetate 作用下， 以 乙醇 为溶剂， 以78%的产率得到
  参考文献：
  名称：

  Synthesis and spectral characterization of Zn(II) microsphere series for antimicrobial application

  摘要：

  Microsphere series have been synthesized by reacting zinc(II) acetate dihydrate with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole/oxadiazole/triazole with salicylaldehyde. Elemental analysis suggests that the complexes have 1:2 and 1:1 stoichiometry of the type [Zn(L)(2)(H2O)(2)] and [Zn(L')(2)(H2O)(2)]; LH = Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thia/oxadiazole with salicylaldehyde; L'H-2 = Schiff bases derived from 3-(substituted phenyl)-4-amino-5-hydrazino-1,2,4-triazole and salicylaldehyde and were characterized by elemental analyses, IR, H-1 NMR and C-13 NMR spectral data. Scanning electron microscopy (SEM) showed that synthesized materials have microsphere like structure and there EDX analysis comparably matches with elemental analysis. For the antimicrobial application Schiff bases and their zinc(II) complexes were screened for four bacteria e.g. Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Streptococcus pyogenes and four fungi e.g. Cyrtomium falcatum, Aspergillus niger, Fusarium oxysporium and Curvularia pallescence by the reported method. Schiff base and Zn(II) compounds showed significant antimicrobial activities. However, activities increase upon chelation. Thermal analysis (TGA) data of compound (10) showed its stability up to 300 degrees C. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2014.06.009
• 作为产物：
  描述：

  苯甲酸 在 硫酸 、 一水合肼 、 potassium hydroxide 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  新型有机磷化合物的合成、结构和真菌毒性

  摘要：

  摘要 通过 O,O-二乙基氯磷酸酯与衍生自 5-(苯基/取代苯基)-2-肼基-1,3,4-恶二唑和水杨醛/2-的席夫碱反应合成了一系列具有生物活性的有机磷化合物。羟基苯乙酮。这些化合物已在分析和光谱（IR、1H、13C NMR）数据的基础上进行了表征。已经评估了这些衍生物对镰状炭疽菌、尖孢镰刀菌和浅色弯孢霉的杀真菌活性。所有化合物均表现出中等至显着的抗真菌活性。图形概要

  DOI：

  10.1080/10426507.2012.681408