| 1237785-44-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• CAS: 1237785-44-2
• 化学式: C₂₈H₃₈N₈O₂Si
• 分子量: 546.748
• InChiKey: XTDHLQOIWVVPLD-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  生成 1-(3-Aminophenyl)-3-[3-[6-(3-hydroxypropylamino)-9-methylpurin-2-yl]phenyl]urea
  参考文献：
  名称：

  Towards Gram-positive antivirulence drugs: New inhibitors of Streptococcus agalactiae Stk1

  摘要：

  A structure-activity relationship study from a screening hit and structure-based design strategy has led to the identification of bisarylureas as potent inhibitors of Streptococcus agalactiae Stk1. As this target has been directly linked to bacterial virulence, these inhibitors can be considered as a promising step towards antivirulence drugs. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.05.004
• 作为产物：
  描述：

  、 间苯二胺 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 生成
  参考文献：
  名称：

  Towards Gram-positive antivirulence drugs: New inhibitors of Streptococcus agalactiae Stk1

  摘要：

  A structure-activity relationship study from a screening hit and structure-based design strategy has led to the identification of bisarylureas as potent inhibitors of Streptococcus agalactiae Stk1. As this target has been directly linked to bacterial virulence, these inhibitors can be considered as a promising step towards antivirulence drugs. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.05.004